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SAM-2 S-adenosylmethionine synthetase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 826987, updated on 19-Feb-2025
Official Symbol
SAM-2
Official Full Name
S-adenosylmethionine synthetase 2
Primary source
TAIR:AT4G01850
Locus tag
AT4G01850
See related
Araport:AT4G01850
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtSAM2; MAT2; S-adenosylmethionine synthetase 2; S-ADENOSYLMETHIONINE SYNTHETASE 2; SAM2; T7B11.11; T7B11_11
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See SAM-2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
2
Sequence:
Chromosome: 4; NC_003075.7 (795986..798381, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene P-glycoprotein 5 Neighboring gene Ca2+ activated outward rectifying K+ channel 5 Neighboring gene Transducin family protein / WD-40 repeat family protein Neighboring gene tRNA-Phe

Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. FERONIA receptor kinase interacts with S-adenosylmethionine synthetase and suppresses S-adenosylmethionine production and ethylene biosynthesis in Arabidopsis. Mao D, et al. Plant Cell Environ, 2015 Dec. PMID 25988356
  2. EXPO, an exocyst-positive organelle distinct from multivesicular endosomes and autophagosomes, mediates cytosol to cell wall exocytosis in Arabidopsis and tobacco cells. Wang J, et al. Plant Cell, 2010 Dec. PMID 21193573, Free PMC Article
  3. Proteomic survey of copper-binding proteins in Arabidopsis roots by immobilized metal affinity chromatography and mass spectrometry. Kung CC, et al. Proteomics, 2006 May. PMID 16526091
  4. Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis. Saracco SA, et al. Plant J, 2009 Jul. PMID 19292762, Free PMC Article
  5. Profiling of the Receptor for Activated C Kinase 1a (RACK1a) interaction network in Arabidopsis thaliana. Guo J, et al. Biochem Biophys Res Commun, 2019 Dec 3. PMID 31606202

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description
NM_001084876.1
NM_116415.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables copper ion binding HDA PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in extracellular exosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus HDA PubMed 
located_in plant-type cell wall HDA PubMed 
located_in plasmodesma HDA PubMed 
Preferred Names
S-adenosylmethionine synthetase 2
NP_001078345.1
  • S-adenosylmethionine synthetase 2 (SAM-2); FUNCTIONS IN: methionine adenosyltransferase activity; INVOLVED IN: one-carbon metabolic process, S-adenosylmethionine biosynthetic process; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: S-adenosylmethionine synthetase (InterPro:IPR002133), S-adenosylmethionine synthetase superfamily (InterPro:IPR022636), S-adenosylmethionine synthetase, N-terminal (InterPro:IPR022628), S-adenosylmethionine synthetase, C-terminal (InterPro:IPR022630), S-adenosylmethionine synthetase, conserved site (InterPro:IPR022631), S-adenosylmethionine synthetase, central domain (InterPro:IPR022629); BEST Arabidopsis thaliana protein match is: S-adenosylmethionine synthetase 1 (TAIR:AT1G02500.2); Has 10906 Blast hits to 10898 proteins in 2898 species: Archae - 12; Bacteria - 5497; Metazoa - 373; Fungi - 167; Plants - 706; Viruses - 1; Other Eukaryotes - 4150 (source: NCBI BLink).
NP_192094.1
  • S-adenosylmethionine synthetase 2 (SAM-2); FUNCTIONS IN: copper ion binding, methionine adenosyltransferase activity; INVOLVED IN: one-carbon metabolic process, S-adenosylmethionine biosynthetic process; LOCATED IN: nucleolus, cell wall; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: S-adenosylmethionine synthetase (InterPro:IPR002133), S-adenosylmethionine synthetase superfamily (InterPro:IPR022636), S-adenosylmethionine synthetase, N-terminal (InterPro:IPR022628), S-adenosylmethionine synthetase, C-terminal (InterPro:IPR022630), S-adenosylmethionine synthetase, conserved site (InterPro:IPR022631), S-adenosylmethionine synthetase, central domain (InterPro:IPR022629); BEST Arabidopsis thaliana protein match is: S-adenosylmethionine synthetase 1 (TAIR:AT1G02500.2); Has 10906 Blast hits to 10898 proteins in 2898 species: Archae - 12; Bacteria - 5497; Metazoa - 373; Fungi - 167; Plants - 706; Viruses - 1; Other Eukaryotes - 4150 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    795986..798381 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_116415.4 → NP_192094.1  S-adenosylmethionine synthetase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_192094.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P17562, Q42263
    UniProtKB/TrEMBL
    A0A178V3V9, A0A5S9XP07
    Conserved Domains (1) summary
    PLN02243
    Location:1 → 386
    PLN02243; S-adenosylmethionine synthase

  2. NM_001084876.1 → NP_001078345.1  S-adenosylmethionine synthetase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078345.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P17562, Q42263
    UniProtKB/TrEMBL
    A0A178V3V9, A0A5S9XP07
    Conserved Domains (1) summary
    PLN02243
    Location:1 → 386
    PLN02243; S-adenosylmethionine synthase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P17562.1

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