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ABCB3 P-glycoprotein 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 826951, updated on 15-Oct-2023

Summary

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Gene symbol
ABCB3
Gene description
P-glycoprotein 3
Primary source
Araport:AT4G01820
Locus tag
AT4G01820
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATP-binding cassette B3; MDR3; P-glycoprotein 3; PGP3; T7B11.8; T7B11_8
Summary
member of MDR subfamily
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Genomic context

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Location:
chromosome: 4
Exon count:
11
Sequence:
Chromosome: 4; NC_003075.7 (780646..785340, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein Neighboring gene Albino or Glassy Yellow 1 Neighboring gene Sec23/Sec24 protein transport family protein Neighboring gene P-glycoprotein 5 Neighboring gene Ca2+ activated outward rectifying K+ channel 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Arabidopsis thaliana ABC protein superfamily, a complete inventory. Sánchez-Fernández R, et al. J Biol Chem, 2001 Aug 10. PMID 11346655
  2. Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. Bellati J, et al. Mol Cell Proteomics, 2016 Nov. PMID 27609422, Free PMC Article
  3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
P-glycoprotein 3
NP_192091.1
  • P-glycoprotein 3 (PGP3); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: integral to membrane; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 5 (TAIR:AT4G01830.1); Has 830190 Blast hits to 386538 proteins in 4151 species: Archae - 14649; Bacteria - 648558; Metazoa - 17709; Fungi - 12207; Plants - 9512; Viruses - 34; Other Eukaryotes - 127521 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    780646..785340 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_116412.2 → NP_192091.1  P-glycoprotein 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_192091.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O49749, Q9SYI2
    UniProtKB/TrEMBL
    A0A654FKZ6
    Conserved Domains (3) summary
    cd03249
    Location:348 → 586
    ABC_MTABC3_MDL1_MDL2; ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins
    PTZ00265
    Location:4 → 1223
    PTZ00265; multidrug resistance protein (mdr1); Provisional
    pfam00664
    Location:30 → 286
    ABC_membrane; ABC transporter transmembrane region

  2. NM_001340338.1 → NP_001328373.1  P-glycoprotein 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B4H4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SYI2.1

Gene LinkOut

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