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PBF1 N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825253, updated on 11-Oct-2018

Summary

Gene symbol
PBF1
Gene description
N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein
Primary source
Araport:AT3G60820
Locus tag
AT3G60820
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
20S PROTEASOME BETA SUBUNIT PBF1
Summary
Encodes 20S proteasome beta subunit PBF1 (PBF1).

Genomic context

See PBF1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
7
Sequence:
Chromosome: 3; NC_003074.8 (22471769..22473971, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene DHHC-type zinc finger family protein Neighboring gene tRNA Neighboring gene DUF1499 family protein Neighboring gene actin-related protein 7 Neighboring gene microtubule-associated protein 65-4

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

NM_001035828.2
NM_001203217.1
NM_115946.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
peptidase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
threonine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
apoplast IDA
Inferred from Direct Assay
more info
PubMed 
chloroplast IDA
Inferred from Direct Assay
more info
PubMed 
chloroplast ISM
Inferred from Sequence Model
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
proteasome complex IDA
Inferred from Direct Assay
more info
PubMed 
proteasome core complex IEA
Inferred from Electronic Annotation
more info
 
proteasome core complex TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein
NP_001030905.1
  • PBF1; FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: defense response to fungus, incompatible interaction, ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex, plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, beta-type subunit, conserved site (InterPro:IPR016050), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: proteasome beta subunit C1 (TAIR:AT1G21720.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_001190146.1
  • PBF1; FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: defense response to fungus, incompatible interaction, ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, beta-type subunit, conserved site (InterPro:IPR016050), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: proteasome beta subunit C1 (TAIR:AT1G21720.1).
NP_191641.1
  • PBF1; FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: defense response to fungus, incompatible interaction, ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex, plasma membrane, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, beta-type subunit, conserved site (InterPro:IPR016050), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: proteasome beta subunit C1 (TAIR:AT1G21720.1); Has 4354 Blast hits to 4354 proteins in 444 species: Archae - 499; Bacteria - 50; Metazoa - 1642; Fungi - 1076; Plants - 489; Viruses - 0; Other Eukaryotes - 598 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    22471769..22473971 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115946.3NP_191641.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191641.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P42742
    UniProtKB/TrEMBL
    A0A178V6R9
    Conserved Domains (2) summary
    COG0638
    Location:10219
    PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
    cd03757
    Location:8223
    proteasome_beta_type_1; proteasome beta type-1 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
  2. NM_001035828.2NP_001030905.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001030905.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4JD01
    Conserved Domains (2) summary
    COG0638
    Location:10219
    PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
    cd03757
    Location:8223
    proteasome_beta_type_1; proteasome beta type-1 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
  3. NM_001203217.1NP_001190146.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190146.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P42742
    UniProtKB/TrEMBL
    A0A178V6R9
    Conserved Domains (2) summary
    COG0638
    Location:10219
    PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
    cd03757
    Location:8223
    proteasome_beta_type_1; proteasome beta type-1 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
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