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2-aminoethanethiol dioxygenase, putative (DUF1637) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825036, updated on 6-Jul-2026
Official Full Name
2-aminoethanethiol dioxygenase, putative (DUF1637)
Primary source
TAIR:AT3G58670
Locus tag
AT3G58670
See related
Araport:AT3G58670
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
PCO5; plant cysteine oxidase 5
Try the new Gene page
Try the new Transcripts and proteins table
Location:
chromosome: 3
Exon count:
6
Sequence:
Chromosome: 3; NC_003074.8 (21703385..21706137, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene GPI-anchored adhesin-like protein Neighboring gene Ribosomal protein L1p/L10e family Neighboring gene multiprotein bridging factor 1B Neighboring gene Protein kinase superfamily protein

Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structures of Arabidopsis thaliana oxygen-sensing plant cysteine oxidases 4 and 5 enable targeted manipulation of their activity. White MD, et al. Proc Natl Acad Sci U S A, 2020 Sep 15. PMID 32868422, Free PMC Article
  2. Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana. Chen Z, et al. J Struct Biol, 2021 Mar. PMID 33207269
  3. The plant cysteine oxidases from Arabidopsis thaliana are kinetically tailored to act as oxygen sensors. White MD, et al. J Biol Chem, 2018 Jul 27. PMID 29848548, Free PMC Article
  4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
  5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

NM_001084841.2
NM_001203199.1
NM_001339929.1
NM_115729.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables cysteine dioxygenase activity EXP
Inferred from Experiment
more info
 PubMed 
enables cysteine dioxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cellular response to hypoxia IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in detection of hypoxia IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in detection of hypoxia IEA
Inferred from Electronic Annotation
more info
  
involved_in peptidyl-cysteine oxidation IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  
Preferred Names
2-aminoethanethiol dioxygenase, putative (DUF1637)
NP_001078310.1
  • Protein of unknown function (DUF1637); FUNCTIONS IN: cysteamine dioxygenase activity; INVOLVED IN: oxidation reduction; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1637 (InterPro:IPR012864); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1637) (TAIR:AT2G42670.1); Has 361 Blast hits to 361 proteins in 94 species: Archae - 0; Bacteria - 0; Metazoa - 103; Fungi - 0; Plants - 221; Viruses - 0; Other Eukaryotes - 37 (source: NCBI BLink).
NP_001190128.1
  • Protein of unknown function (DUF1637); FUNCTIONS IN: cysteamine dioxygenase activity; INVOLVED IN: oxidation reduction; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1637 (InterPro:IPR012864); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1637) (TAIR:AT2G42670.1).
NP_191426.1
  • Protein of unknown function (DUF1637); FUNCTIONS IN: cysteamine dioxygenase activity; INVOLVED IN: oxidation reduction; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1637 (InterPro:IPR012864); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1637) (TAIR:AT2G42670.1); Has 361 Blast hits to 361 proteins in 94 species: Archae - 0; Bacteria - 0; Metazoa - 103; Fungi - 0; Plants - 221; Viruses - 0; Other Eukaryotes - 37 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    21703385..21706137 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115729.4 → NP_191426.1  2-aminoethanethiol dioxygenase, putative (DUF1637) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191426.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LXT4
    Conserved Domains (1) summary
    pfam07847
    Location:33 → 240
    PCO_ADO

  2. NM_001339929.1 → NP_001326765.1  2-aminoethanethiol dioxygenase, putative (DUF1637) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LQA0

  3. NM_001084841.2 → NP_001078310.1  2-aminoethanethiol dioxygenase, putative (DUF1637) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078310.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LXT4
    Conserved Domains (1) summary
    pfam07847
    Location:33 → 240
    PCO_ADO

  4. NM_001203199.1 → NP_001190128.1  2-aminoethanethiol dioxygenase, putative (DUF1637) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190128.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LXT4
    Conserved Domains (1) summary
    pfam07847
    Location:33 → 240
    PCO_ADO
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LXT4.1

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