AP3 K-box region and MADS-box transcription factor family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: AP3
Gene description: K-box region and MADS-box transcription factor family protein
Primary source: Araport:AT3G54340
Locus tag: AT3G54340
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: APETALA 3; ATAP3; FLORAL HOMEOTIC PROTEIN APETALA 3
Summary: Floral homeotic gene encoding a MADS domain protein homologous to SRF transcription factors. Specifies petal and stamen identities. Associates with PISTILLATA.
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Genomic context

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Location:: chromosome: 3

Exon count:: 7

Sequence:: Chromosome: 3; NC_003074.8 (20119140..20121314, complement)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

My favourite flowering image: an Arabidopsis inflorescence expressing fluorescent reporters for the APETALA3 and SUPERMAN genes.
Title: My favourite flowering image: an Arabidopsis inflorescence expressing fluorescent reporters for the APETALA3 and SUPERMAN genes.
The expression of AP3 was reactivated and the methylation level of AP3 promoter was also reduced in RNA-Directed DNA Methylation-defective AP3-silencing lines.
Title: Exogenous Promoter Triggers APETALA3 Silencing through RNA-Directed DNA Methylation Pathway in Arabidopsis.
Ectopic Fagopyrum esculentum AP3 can rescue stamen development in Arabidopsis ap3 mutant.
Title: Ectopic expression of FaesAP3, a Fagopyrum esculentum (Polygonaceae) AP3 orthologous gene rescues stamen development in an Arabidopsis ap3 mutant.
Data indicate that C function regulator AGAMOUS and the B function regulators APETALA3 and PISTILLATA control many developmental processes in conjunction, as well as independent activities.
Title: Control of reproductive floral organ identity specification in Arabidopsis by the C function regulator AGAMOUS.
These results imply considerable changes in the composition and topology of the gene network controlled by AP3/PI during the course of flower development.
Title: Molecular basis for the specification of floral organs by APETALA3 and PISTILLATA.
BNQ genes Are negatively regulated by AP3 and PI in petals.
Title: The Arabidopsis floral homeotic proteins APETALA3 and PISTILLATA negatively regulate the BANQUO genes implicated in light signaling.
truncated form, lacking the conserved C-terminal motifs, functions to direct floral organ identity specification
Title: Conserved C-terminal motifs of the Arabidopsis proteins APETALA3 and PISTILLATA are dispensable for floral organ identity function.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_115294.6

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within specification of floral organ identity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in specification of floral organ identity	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: K-box region and MADS-box transcription factor family protein

NP_191002.1

APETALA 3 (AP3); CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100), Transcription factor, K-box (InterPro:IPR002487); BEST Arabidopsis thaliana protein match is: AGAMOUS-like 71 (TAIR:AT5G51870.1); Has 6838 Blast hits to 6837 proteins in 855 species: Archae - 0; Bacteria - 0; Metazoa - 626; Fungi - 302; Plants - 5820; Viruses - 0; Other Eukaryotes - 90 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

20119140..20121314 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_115294.6 → NP_191002.1 K-box region and MADS-box transcription factor family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_191002.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P35632, Q39003, Q8LB79, Q9S7Q3, Q9SQ14, Q9SQ15, Q9SQ16, Q9SQ17, Q9SQ18, Q9SQ19, Q9SQ20, Q9SQ21, Q9SQ22, Q9SX13

UniProtKB/TrEMBL

A0A178VHZ2, A0A5S9XL06, A0A7G2ESU4

Conserved Domains (2) summary

cd00265
Location:2 → 80

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam01486
Location:81 → 169

K-box; K-box region