AHP2 histidine-containing phosphotransmitter 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: AHP2
Official Full Name: histidine-containing phosphotransmitter 2
Primary source: TAIR:AT3G29350
Locus tag: AT3G29350
See related: Araport:AT3G29350
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: histidine-containing phosphotransmitter 2
Summary: Encodes AHP2, one of the six Arabidopsis thaliana histidine phosphotransfer proteins (AHPs). AHPs function in His-to-Asp phosphorelay signal transduction and as redundant positive regulators of cytokinin signaling. Members of the AHP gene family include: AT3G21510 (AHP1), AT3G29350 (AHP2), AT5G39340 (AHP3), AT3G16360 (AHP4), AT1G03430 (AHP5) and AT1G80100 (AHP6).
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Genomic context

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See AHP2 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 6

Sequence:: Chromosome: 3; NC_003074.8 (11264126..11265562, complement)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AHP2 is present in the nucleus and the cytoplasm, and is involved in light-induced stomata opening.The AHP2 gene is expressed in guard cells.
Title: Involvement of two-component signalling systems in the regulation of stomatal aperture by light in Arabidopsis thaliana.
The three-dimensional structure of AHP2 was determined.
Title: Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of AHP2, a signal transmitter protein from Arabidopsis thaliana.
ARR1 mediates cold signal via AHP2 (Arabidopsis histidine kinase 2), AHP3, or AHP5.
Title: Arabidopsis response Regulator1 and Arabidopsis histidine phosphotransfer Protein2 (AHP2), AHP3, and AHP5 function in cold signaling.
Arabidopsis AHP2, AHP3, and AHP5 histidine phosphotransfer proteins function as redundant negative regulators of drought stress response.
Title: Arabidopsis AHP2, AHP3, and AHP5 histidine phosphotransfer proteins function as redundant negative regulators of drought stress response.
findings suggest that the presence of Ahp2 protein is necessary for alignment stabilization and synapsis of most chromosome regions but is not required for initial close juxtapositions of homologous chromosomes
Title: Ahp2 (Hop2) function in Arabidopsis thaliana (Ler) is required for stabilization of close alignment and synaptonemal complex formation except for the two short arms that contain nucleolus organizer regions.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_113860.4

Supported by ESTs:

NM_180318.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables histidine phosphotransfer kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables histidine phosphotransfer kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables histidine phosphotransfer kinase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein histidine kinase binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein histidine kinase binding	IEA Inferred from Electronic Annotation more info
enables protein histidine kinase binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within antipodal cell differentiation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in cytokinin-activated signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in cytokinin-activated signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cytokinin-activated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cytokinin-activated signaling pathway	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within embryo sac egg cell differentiation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in phosphorelay signal transduction system	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phosphorelay signal transduction system	IDA Inferred from Direct Assay more info	PubMed
involved_in phosphorelay signal transduction system	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	NAS Non-traceable Author Statement more info	PubMed
located_in cytosol	HDA more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: histidine-containing phosphotransmitter 2

NP_189581.1

histidine-containing phosphotransmitter 2 (AHP2); CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, phosphotransfer (Hpt) domain (InterPro:IPR008207); BEST Arabidopsis thaliana protein match is: histidine-containing phosphotransmitter 3 (TAIR:AT5G39340.1); Has 369 Blast hits to 368 proteins in 74 species: Archae - 2; Bacteria - 69; Metazoa - 0; Fungi - 28; Plants - 267; Viruses - 0; Other Eukaryotes - 3 (source: NCBI BLink).

NP_850649.1

histidine-containing phosphotransmitter 2 (AHP2); CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, phosphotransfer (Hpt) domain (InterPro:IPR008207); BEST Arabidopsis thaliana protein match is: histidine-containing phosphotransmitter 3 (TAIR:AT5G39340.1); Has 298 Blast hits to 297 proteins in 39 species: Archae - 2; Bacteria - 10; Metazoa - 0; Fungi - 21; Plants - 263; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

11264126..11265562 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_113860.4 → NP_189581.1 histidine-containing phosphotransmitter 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_189581.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q3EAX3, Q9ZNV8

Conserved Domains (1) summary

pfam01627
Location:46 → 130

Hpt; Hpt domain
NM_180318.2 → NP_850649.1 histidine-containing phosphotransmitter 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_850649.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9ZNV8

Conserved Domains (1) summary

cd00088
Location:44 → 111

HPT; Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is ...