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HSP60 heat shock protein 60 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821983, updated on 11-Oct-2018

Summary

Gene symbol
HSP60
Gene description
heat shock protein 60
Primary source
Araport:AT3G23990
Locus tag
AT3G23990
Gene type
protein coding
RNA name
heat shock protein 60
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
heat shock protein 60; HEAT SHOCK PROTEIN 60-3B; HSP60-3B
Summary
mitochondrial chaperonin HSP. assist in rapid assembly of the oligomeric protein structures in the mitochondria.

Genomic context

See HSP60 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
16
Sequence:
Chromosome: 3; NC_003074.8 (8668772..8672578)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box family protein Neighboring gene BLISTER Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene miscRNA

Pathways from BioSystems

  • RNA degradation, organism-specific biosystem (from KEGG)
    RNA degradation, organism-specific biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
  • RNA degradation, conserved biosystem (from KEGG)
    RNA degradation, conserved biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

NM_113304.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
ATP binding IDA
Inferred from Direct Assay
more info
PubMed 
copper ion binding IDA
Inferred from Direct Assay
more info
PubMed 
unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
'de novo' protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chaperone-mediated protein complex assembly TAS
Traceable Author Statement
more info
 
mitochondrion organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion organization TAS
Traceable Author Statement
more info
PubMed 
protein import into mitochondrial intermembrane space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein refolding IEA
Inferred from Electronic Annotation
more info
 
response to cadmium ion IEP
Inferred from Expression Pattern
more info
PubMed 
response to heat IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
NOT Golgi apparatus RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
chloroplast ISM
Inferred from Sequence Model
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
NOT cytosol RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
cytosolic ribosome IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
vacuolar membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
heat shock protein 60
NP_189041.1
  • heat shock protein 60 (HSP60); FUNCTIONS IN: copper ion binding, ATP binding; INVOLVED IN: response to cadmium ion, response to cyclopentenone, chaperone-mediated protein complex assembly, response to heat, mitochondrion organization; LOCATED IN: cytosol, cytosolic ribosome, mitochondrion, plasma membrane, mitochondrial matrix; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Chaperonin Cpn60/TCP-1 (InterPro:IPR002423), Chaperonin Cpn60, conserved site (InterPro:IPR018370), Chaperonin Cpn60 (InterPro:IPR001844); BEST Arabidopsis thaliana protein match is: heat shock protein 60-2 (TAIR:AT2G33210.1); Has 33706 Blast hits to 33652 proteins in 8680 species: Archae - 676; Bacteria - 21745; Metazoa - 1618; Fungi - 1515; Plants - 790; Viruses - 2; Other Eukaryotes - 7360 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    8668772..8672578
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_113304.5NP_189041.1  heat shock protein 60 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_189041.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29197
    UniProtKB/TrEMBL
    A0A178VEN0
    Conserved Domains (2) summary
    PTZ00114
    Location:20559
    PTZ00114; Heat shock protein 60; Provisional
    cd03344
    Location:34554
    GroEL; GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found ...
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