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DMC1 DNA repair (Rad51) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821860, updated on 11-Oct-2018

Summary

Gene symbol
DMC1
Gene description
DNA repair (Rad51) family protein
Primary source
Araport:AT3G22880
Locus tag
AT3G22880
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS HOMOLOG OF LILY MESSAGES INDUCED AT MEIOSIS 15; ARABIDOPSIS THALIANA DISRUPTION OF MEIOTIC CONTROL 1; ARLIM15; ATDMC1; DISRUPTION OF MEIOTIC CONTROL 1
Summary
Expression of the AtDMC1 is restricted to pollen mother cells in anthers and to megaspore mother cells in ovules. Similar to meiosis-specific yeast DMC gene.

Genomic context

See DMC1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
15
Sequence:
Chromosome: 3; NC_003074.8 (8097678..8100932, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3 subunit C2 Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

NM_001338602.1
NM_113188.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATP binding ISS
Inferred from Sequence or Structural Similarity
more info
 
DNA-dependent ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-dependent ATPase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
damaged DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
recombinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
DNA metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
DNA recombinase assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA repair ISS
Inferred from Sequence or Structural Similarity
more info
 
chiasma assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
chiasma assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
meiotic cell cycle TAS
Traceable Author Statement
more info
PubMed 
mitotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
reciprocal meiotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
reciprocal meiotic recombination ISS
Inferred from Sequence or Structural Similarity
more info
 
strand invasion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
condensed nuclear chromosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
DNA repair (Rad51) family protein
NP_188928.2
  • DISRUPTION OF MEIOTIC CONTROL 1 (DMC1); FUNCTIONS IN: in 6 functions; INVOLVED IN: DNA repair, meiosis, chiasma assembly, reciprocal meiotic recombination, DNA metabolic process; LOCATED IN: nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: DNA recombination/repair protein RecA/RadB, ATP-binding domain (InterPro:IPR020588), DNA repair Rad51/transcription factor NusA, alpha-helical (InterPro:IPR010995), ATPase, AAA+ type, core (InterPro:IPR003593), Meiotic recombinase Dmc1 (InterPro:IPR011940), DNA recombination and repair protein, RecA-like (InterPro:IPR016467), DNA recombination/repair protein RecA, monomer-monomer interface (InterPro:IPR020587), DNA recombination and repair protein Rad51, C-terminal (InterPro:IPR013632); BEST Arabidopsis thaliana protein match is: RAS associated with diabetes protein 51 (TAIR:AT5G20850.1); Has 11998 Blast hits to 11924 proteins in 3797 species: Archae - 689; Bacteria - 8026; Metazoa - 742; Fungi - 447; Plants - 503; Viruses - 22; Other Eukaryotes - 1569 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    8097678..8100932 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_113188.3NP_188928.2  DNA repair (Rad51) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_188928.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q39009
    UniProtKB/TrEMBL
    A0A178VEK4
    Conserved Domains (3) summary
    PLN03187
    Location:1344
    PLN03187; meiotic recombination protein DMC1 homolog; Provisional
    cd01123
    Location:108339
    Rad51_DMC1_radA; Rad51_DMC1_radA,B. This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal proteins radA and radB. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a ...
    pfam14520
    Location:3886
    HHH_5; Helix-hairpin-helix domain
  2. NM_001338602.1NP_001327749.1  DNA repair (Rad51) family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LT97
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