U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PAS_chr2-1_0391 Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide [ Komagataella phaffii GS115 ]

Gene ID: 8198859, updated on 23-Nov-2023

Summary

Go to the top of the page Help
Gene symbol
PAS_chr2-1_0391
Gene description
Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide
Locus tag
PAS_chr2-1_0391
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Komagataella phaffii GS115 (strain: GS115)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Phaffomycetaceae; Komagataella
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 2
Exon count:
2
Sequence:
Chromosome: 2; NC_012964.1 (721942..724108)

Chromosome 2 - NC_012964.1Genomic Context describing neighboring genes Neighboring gene Subunit of tRNA-specific adenosine-34 deaminase Neighboring gene Sorting nexin Neighboring gene Protein with similarity to the p27 subunit of mammalian proteasome modulator Neighboring gene Ubiquitin-like protein with weak sequence similarity to ubiquitin

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_012964.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genome sequence of the recombinant protein production host Pichia pastoris. De Schutter K, et al. Nat Biotechnol, 2009 Jun. PMID 19465926

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables lanosterol synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ergosterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in triterpenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_012964.1 Reference assembly

    Range
    721942..724108
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002491247.1 → XP_002491292.1  Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide [Komagataella phaffii GS115]

    See identical proteins and their annotated locations for XP_002491292.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    C4R0I8, F2QT61
    Conserved Domains (2) summary
    cd02892
    Location:72 → 695
    SQCY_1; Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization ...
    TIGR01787
    Location:71 → 697
    squalene_cyclas; squalene/oxidosqualene cyclases
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases