U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MEE32 dehydroquinate dehydratase, putative / shikimate dehydrogenase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819809, updated on 19-Feb-2025
Official Symbol
MEE32
Official Full Name
dehydroquinate dehydratase, putative / shikimate dehydrogenase
Primary source
TAIR:AT3G06350
Locus tag
AT3G06350
See related
Araport:AT3G06350
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
EMB3004; EMBRYO DEFECTIVE 3004; F24P17.18; F24P17_18; MATERNAL EFFECT EMBRYO ARREST 32
Summary
Encodes a bi-functional dehydroquinate-shikimate dehydrogenase enzyme that catalyzes two steps in the chorismate biosynthesis pathway.
Try the new Gene page
Try the new Transcripts and proteins table
See MEE32 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
11
Sequence:
Chromosome: 3; NC_003074.8 (1924270..1927850, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene tRNA-Pro Neighboring gene DNAJ heat shock N-terminal domain-containing protein Neighboring gene arabinogalactan protein 27 Neighboring gene sodium hydrogen exchanger 4

Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structure of Arabidopsis dehydroquinate dehydratase-shikimate dehydrogenase and implications for metabolic channeling in the shikimate pathway. Singh SA, et al. Biochemistry, 2006 Jun 27. PMID 16784230
  2. Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis. Pagnussat GC, et al. Development, 2005 Feb. PMID 15634699
  3. Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis. Rutschow H, et al. Plant Physiol, 2008 Sep. PMID 18633119, Free PMC Article
  4. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475
  5. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description
NM_111510.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 3-dehydroquinate dehydratase activity IDA
Inferred from Direct Assay
more info
  
enables shikimate 3-dehydrogenase (NADP+) activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within embryo development ending in seed dormancy NAS
Non-traceable Author Statement
more info
  
acts_upstream_of_or_within shikimate metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma HDA PubMed 
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Preferred Names
dehydroquinate dehydratase, putative / shikimate dehydrogenase
NP_187286.1
  • MATERNAL EFFECT EMBRYO ARREST 32 (MEE32); FUNCTIONS IN: NADP or NADPH binding, 3-dehydroquinate dehydratase activity, shikimate 5-dehydrogenase activity, binding, catalytic activity; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase (InterPro:IPR006151), Aldolase-type TIM barrel (InterPro:IPR013785), Quinate/shikimate 5-dehydrogenase (InterPro:IPR011342), NAD(P)-binding domain (InterPro:IPR016040), Dehydroquinase class I (InterPro:IPR001381), Shikimate dehydrogenase substrate binding, N-terminal (InterPro:IPR013708); Has 14455 Blast hits to 14453 proteins in 2669 species: Archae - 507; Bacteria - 10604; Metazoa - 0; Fungi - 391; Plants - 114; Viruses - 0; Other Eukaryotes - 2839 (source: NCBI BLink).

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    1924270..1927850 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111510.4 → NP_187286.1  dehydroquinate dehydratase, putative / shikimate dehydrogenase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187286.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3ZLP7, Q56ZH7, Q6NLY1, Q9SQT8
    UniProtKB/TrEMBL
    A0A178VBC4, A0A5S9XAA2
    Conserved Domains (1) summary
    PLN02520
    Location:72 → 603
    PLN02520; bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SQT8.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools