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HDHD3 haloacid dehalogenase like hydrolase domain containing 3 [ Homo sapiens (human) ]

Gene ID: 81932, updated on 13-Mar-2020

Summary

Official Symbol
HDHD3provided by HGNC
Official Full Name
haloacid dehalogenase like hydrolase domain containing 3provided by HGNC
Primary source
HGNC:HGNC:28171
See related
Ensembl:ENSG00000119431
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C9orf158; 2810435D12Rik
Expression
Ubiquitous expression in duodenum (RPKM 36.7), adrenal (RPKM 34.5) and 25 other tissues See more
Orthologs

Genomic context

See HDHD3 in Genome Data Viewer
Location:
9q32
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (113373416..113376986, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (116135698..116139289, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene WD repeat domain 31 Neighboring gene B-box and SPRY domain containing Neighboring gene aminolevulinate dehydratase Neighboring gene DNA polymerase epsilon 3, accessory subunit Neighboring gene chromosome 9 open reading frame 43

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC12904

Gene Ontology Provided by GOA

Function Evidence Code Pubs
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
nucleolus IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
haloacid dehalogenase-like hydrolase domain-containing protein 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304509.2NP_001291438.1  haloacid dehalogenase-like hydrolase domain-containing protein 3

    See identical proteins and their annotated locations for NP_001291438.1

    Status: VALIDATED

    Source sequence(s)
    AK315401, BC031878, CN281644
    Consensus CDS
    CCDS6793.1
    UniProtKB/Swiss-Prot
    Q9BSH5
    Related
    ENSP00000363295.3, ENST00000374180.3
    Conserved Domains (1) summary
    TIGR02252
    Location:8210
    DREG-2; REG-2-like, HAD superfamily (subfamily IA) hydrolase
  2. NM_001304510.2NP_001291439.1  haloacid dehalogenase-like hydrolase domain-containing protein 3

    See identical proteins and their annotated locations for NP_001291439.1

    Status: VALIDATED

    Source sequence(s)
    BC031878, CN281644, DA964284
    Consensus CDS
    CCDS6793.1
    UniProtKB/Swiss-Prot
    Q9BSH5
    Conserved Domains (1) summary
    TIGR02252
    Location:8210
    DREG-2; REG-2-like, HAD superfamily (subfamily IA) hydrolase
  3. NM_001304511.2NP_001291440.1  haloacid dehalogenase-like hydrolase domain-containing protein 3

    See identical proteins and their annotated locations for NP_001291440.1

    Status: VALIDATED

    Source sequence(s)
    BC031878, CD515020, CN281644
    Consensus CDS
    CCDS6793.1
    UniProtKB/Swiss-Prot
    Q9BSH5
    Conserved Domains (1) summary
    TIGR02252
    Location:8210
    DREG-2; REG-2-like, HAD superfamily (subfamily IA) hydrolase
  4. NM_001371923.1NP_001358852.1  haloacid dehalogenase-like hydrolase domain-containing protein 3

    Status: VALIDATED

    Source sequence(s)
    AL137066
  5. NM_031219.4NP_112496.1  haloacid dehalogenase-like hydrolase domain-containing protein 3

    See identical proteins and their annotated locations for NP_112496.1

    Status: VALIDATED

    Source sequence(s)
    AL137066
    Consensus CDS
    CCDS6793.1
    UniProtKB/Swiss-Prot
    Q9BSH5
    Related
    ENSP00000238379.5, ENST00000238379.9
    Conserved Domains (1) summary
    TIGR02252
    Location:8210
    DREG-2; REG-2-like, HAD superfamily (subfamily IA) hydrolase

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    113373416..113376986 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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