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ZNF93 zinc finger protein 93 [ Homo sapiens (human) ]

Gene ID: 81931, updated on 23-Nov-2021

Summary

Official Symbol
ZNF93provided by HGNC
Official Full Name
zinc finger protein 93provided by HGNC
Primary source
HGNC:HGNC:13169
See related
Ensembl:ENSG00000184635 MIM:603975
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TF34; HPF34; HTF34; ZNF505
Expression
Ubiquitous expression in thyroid (RPKM 2.7), urinary bladder (RPKM 1.7) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF93 in Genome Data Viewer
Location:
19p12
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (19900946..19935575)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (20011755..20046384)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene BCL2 interacting protein 3 pseudogene 9 Neighboring gene zinc finger protein 253 Neighboring gene BCL2 interacting protein 3 pseudogene 10 Neighboring gene BCL2 interacting protein 3 pseudogene 12 Neighboring gene vomeronasal 1 receptor 77 pseudogene Neighboring gene zinc finger protein 682 Neighboring gene uncharacterized LOC105372308

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide and candidate gene association study of cigarette smoking behaviors.
GeneReviews: Not available

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of zinc finger protein 93 (ZNF93) by siRNA enhances the early stages of HIV-1 replication in HeLa-CD4 cells infected with viral pseudotypes HIV89.6R and HIV8.2N PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

General protein information

Preferred Names
zinc finger protein 93
Names
zinc finger protein 505
zinc finger protein HTF34

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031218.4NP_112495.2  zinc finger protein 93

    See identical proteins and their annotated locations for NP_112495.2

    Status: VALIDATED

    Source sequence(s)
    AC007204, BC070372, BC136718
    Consensus CDS
    CCDS32973.1
    UniProtKB/Swiss-Prot
    P35789
    UniProtKB/TrEMBL
    Q6NS90
    Related
    ENSP00000342002.4, ENST00000343769.6
    Conserved Domains (5) summary
    smart00349
    Location:462
    KRAB; krueppel associated box
    COG5048
    Location:170612
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:455475
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:643
    KRAB; KRAB box
    pfam13465
    Location:384408
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    19900946..19935575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001004126.1: Suppressed sequence

    Description
    NM_001004126.1: This RefSeq was permanently suppressed because its 3' exon including the coding region hits an Alu repeat and the C-terminus of the protein is not supported by any other proteins in the database.
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