Format

Send to:

Choose Destination

ARP apurinic endonuclease-redox protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818744, updated on 22-Feb-2019

Summary

Gene symbol
ARP
Gene description
apurinic endonuclease-redox protein
Primary source
Araport:AT2G41460
Locus tag
AT2G41460
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
apurinic endonuclease-redox protein; T26J13.5; T26J13_5
Summary
apurinic endonuclease-redox protein. It functions as an apurinic/apyrimidinic class II endonuclease, and is involved in DNA repair.

Genomic context

See ARP in Genome Data Viewer
Location:
chromosome: 2
Exon count:
12
Sequence:
Chromosome: 2; NC_003071.7 (17285470..17289023)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase Neighboring gene glycosyltransferase-like protein Neighboring gene ncRNA Neighboring gene agamous-like MADS-box protein Neighboring gene F-box family protein

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Homology

NM_001125028.1
NM_001336913.1
NM_001336914.1
NM_129709.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
3'-5' exonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-(apurinic or apyrimidinic site) endonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
class I DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
Inferred from Electronic Annotation
more info
 
endonuclease activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
phosphodiesterase I activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
DNA repair IEA
Inferred from Electronic Annotation
more info
 
nucleotide-excision repair, DNA incision IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
chloroplast nucleoid IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
apurinic endonuclease-redox protein
NP_001118500.1
  • apurinic endonuclease-redox protein (ARP); CONTAINS InterPro DOMAIN/s: DNA-binding SAP (InterPro:IPR003034), AP endonuclease, family 1, binding site (InterPro:IPR020847), Exodeoxyribonuclease III xth (InterPro:IPR004808), Endonuclease/exonuclease/phosphatase (InterPro:IPR005135); BEST Arabidopsis thaliana protein match is: C2 calcium/lipid-binding endonuclease/exonuclease/phosphatase (TAIR:AT3G60950.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_181677.1
  • apurinic endonuclease-redox protein (ARP); CONTAINS InterPro DOMAIN/s: AP endonuclease, family 1, conserved site (InterPro:IPR020848), DNA-binding SAP (InterPro:IPR003034), AP endonuclease, family 1 (InterPro:IPR000097), AP endonuclease, family 1, binding site (InterPro:IPR020847), Endonuclease/exonuclease/phosphatase (InterPro:IPR005135), Exodeoxyribonuclease III xth (InterPro:IPR004808); BEST Arabidopsis thaliana protein match is: C2 calcium/lipid-binding endonuclease/exonuclease/phosphatase (TAIR:AT3G60950.1); Has 8976 Blast hits to 8966 proteins in 2340 species: Archae - 119; Bacteria - 5352; Metazoa - 387; Fungi - 388; Plants - 165; Viruses - 2; Other Eukaryotes - 2563 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    17285470..17289023
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129709.5NP_181677.1  apurinic endonuclease-redox protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181677.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P45951
    UniProtKB/TrEMBL
    A0A178VMT4
    Conserved Domains (3) summary
    smart00513
    Location:97131
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd09087
    Location:277534
    Ape1-like_AP-endo; Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases
    pfam06459
    Location:80234
    RR_TM4-6; Ryanodine Receptor TM 4-6
  2. NM_001336913.1NP_001323447.1  apurinic endonuclease-redox protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AX84
  3. NM_001125028.1NP_001118500.1  apurinic endonuclease-redox protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001118500.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3H7C2
    Conserved Domains (3) summary
    smart00513
    Location:97131
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    pfam06459
    Location:80234
    RR_TM4-6; Ryanodine Receptor TM 4-6
    cl00490
    Location:277400
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
  4. NM_001336914.1NP_001323448.1  apurinic endonuclease-redox protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AX21
Support Center