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ARPC5L actin related protein 2/3 complex subunit 5 like [ Homo sapiens (human) ]

Gene ID: 81873, updated on 9-Feb-2020

Summary

Official Symbol
ARPC5Lprovided by HGNC
Official Full Name
actin related protein 2/3 complex subunit 5 likeprovided by HGNC
Primary source
HGNC:HGNC:23366
See related
Ensembl:ENSG00000136950
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ARC16-2
Expression
Ubiquitous expression in bone marrow (RPKM 7.9), testis (RPKM 7.3) and 25 other tissues See more
Orthologs

Genomic context

See ARPC5L in Genome Data Viewer
Location:
9q33.3
Exon count:
7
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (124862130..124877733)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (127626267..127640012)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene olfactomedin like 2A Neighboring gene WD repeat domain 38 Neighboring gene ribosomal protein L35 Neighboring gene RNA, U4 small nuclear 82, pseudogene Neighboring gene golgin A1 Neighboring gene suppressor of cancer cell invasion Neighboring gene frataxin pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC3038

Gene Ontology Provided by GOA

Function Evidence Code Pubs
actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
Arp2/3 complex-mediated actin nucleation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
biological_process ND
No biological Data available
more info
 
cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
Arp2/3 protein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular exosome HDA PubMed 
focal adhesion HDA PubMed 
glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
actin-related protein 2/3 complex subunit 5-like protein
Names
arp2/3 complex 16 kDa subunit 2
epididymis secretory sperm binding protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030978.3NP_112240.1  actin-related protein 2/3 complex subunit 5-like protein

    See identical proteins and their annotated locations for NP_112240.1

    Status: VALIDATED

    Source sequence(s)
    AA731112, AK056174, AL354928
    Consensus CDS
    CCDS6859.1
    UniProtKB/Swiss-Prot
    Q9BPX5
    UniProtKB/TrEMBL
    A0A024R897, B3KPC7
    Related
    ENSP00000345361.2, ENST00000353214.6
    Conserved Domains (1) summary
    pfam04699
    Location:10150
    P16-Arc; ARP2/3 complex 16 kDa subunit (p16-Arc)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    124862130..124877733
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011519067.1XP_011517369.1  actin-related protein 2/3 complex subunit 5-like protein isoform X1

    See identical proteins and their annotated locations for XP_011517369.1

    Conserved Domains (1) summary
    pfam04699
    Location:199
    P16-Arc; ARP2/3 complex 16 kDa subunit (p16-Arc)

RNA

  1. XR_001746387.1 RNA Sequence

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