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ZNF611 zinc finger protein 611 [ Homo sapiens (human) ]

Gene ID: 81856, updated on 12-Oct-2019

Summary

Official Symbol
ZNF611provided by HGNC
Official Full Name
zinc finger protein 611provided by HGNC
Primary source
HGNC:HGNC:28766
See related
Ensembl:ENSG00000213020
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in kidney (RPKM 2.4), thyroid (RPKM 2.3) and 25 other tissues See more
Orthologs

Genomic context

See ZNF611 in Genome Data Viewer
Location:
19q13.41
Exon count:
9
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (52702813..52735054, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (53206066..53238307, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 701 Neighboring gene zinc finger protein 137, pseudogene Neighboring gene zinc finger protein 83 Neighboring gene uncharacterized LOC105372452 Neighboring gene uncharacterized LOC105372451 Neighboring gene zinc finger protein 600

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from BioSystems

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC5384

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001161499.2NP_001154971.1  zinc finger protein 611 isoform a

    See identical proteins and their annotated locations for NP_001154971.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same isoform (a).
    Source sequence(s)
    AC022150, BC028590, DA226106, DA245006, DA726181
    Consensus CDS
    CCDS12855.1
    UniProtKB/Swiss-Prot
    Q8N823
    Related
    ENSP00000498713.1, ENST00000652185.1
    Conserved Domains (5) summary
    smart00349
    Location:2460
    KRAB; krueppel associated box
    COG5048
    Location:256698
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:540560
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2460
    KRAB; KRAB box
    pfam13465
    Location:665689
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001161500.1NP_001154972.1  zinc finger protein 611 isoform a

    See identical proteins and their annotated locations for NP_001154972.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same isoform (a).
    Source sequence(s)
    AC022150, BC028590, DB122407
    Consensus CDS
    CCDS12855.1
    UniProtKB/Swiss-Prot
    Q8N823
    Related
    ENSP00000439211.1, ENST00000540744.5
    Conserved Domains (5) summary
    smart00349
    Location:2460
    KRAB; krueppel associated box
    COG5048
    Location:256698
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:540560
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2460
    KRAB; KRAB box
    pfam13465
    Location:665689
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001161501.1NP_001154973.1  zinc finger protein 611 isoform b

    See identical proteins and their annotated locations for NP_001154973.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (b) is shorter than isoform a.
    Source sequence(s)
    AC022150, BC028590, DA225124
    Consensus CDS
    CCDS54312.1
    UniProtKB/Swiss-Prot
    Q8N823
    Related
    ENSP00000443505.1, ENST00000453741.6
    Conserved Domains (3) summary
    COG5048
    Location:187629
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:471491
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:596620
    zf-H2C2_2; Zinc-finger double domain
  4. NM_030972.3NP_112234.3  zinc finger protein 611 isoform a

    See identical proteins and their annotated locations for NP_112234.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC022150, AK097434, BC028590, BC143996
    Consensus CDS
    CCDS12855.1
    UniProtKB/Swiss-Prot
    Q8N823
    Related
    ENSP00000322427.1, ENST00000319783.5
    Conserved Domains (5) summary
    smart00349
    Location:2460
    KRAB; krueppel associated box
    COG5048
    Location:256698
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:540560
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2460
    KRAB; KRAB box
    pfam13465
    Location:665689
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    52702813..52735054 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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