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Actb actin, beta [ Rattus norvegicus (Norway rat) ]

Gene ID: 81822, updated on 10-Oct-2019

Summary

Official Symbol
Actbprovided by RGD
Official Full Name
actin, betaprovided by RGD
Primary source
RGD:628837
See related
Ensembl:ENSRNOG00000034254
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Actx
Summary
mRNA expression increases following axon injury; may play a role in acceleration of axonal outgrowth [RGD, Feb 2006]
Expression
Biased expression in Spleen (RPKM 10008.1), Thymus (RPKM 8289.8) and 9 other tissues See more
Orthologs

Genomic context

See Actb in Genome Data Viewer
Location:
12p11
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (13715843..13718813)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 12 NC_005111.3 (15745856..15749440)

Chromosome 12 - NC_005111.4Genomic Context describing neighboring genes Neighboring gene ring finger protein 216 Neighboring gene fascin actin-bundling protein 1 Neighboring gene F-box and leucine-rich repeat protein 18 Neighboring gene uncharacterized LOC108352424

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
Tat protein binding IEA
Inferred from Electronic Annotation
more info
 
Tat protein binding ISO
Inferred from Sequence Orthology
more info
PubMed 
identical protein binding IEA
Inferred from Electronic Annotation
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
PubMed 
kinesin binding IEA
Inferred from Electronic Annotation
more info
 
kinesin binding ISO
Inferred from Sequence Orthology
more info
PubMed 
nitric-oxide synthase binding IEA
Inferred from Electronic Annotation
more info
 
nitric-oxide synthase binding ISO
Inferred from Sequence Orthology
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein kinase binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
PubMed 
structural constituent of postsynaptic actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
structural constituent of postsynaptic actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
structural constituent of postsynaptic actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
axonogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
axonogenesis IDA
Inferred from Direct Assay
more info
PubMed 
cell motility IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell motility IEA
Inferred from Electronic Annotation
more info
 
cell motility ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to cytochalasin B IEA
Inferred from Electronic Annotation
more info
 
cellular response to cytochalasin B ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to electrical stimulus IDA
Inferred from Direct Assay
more info
PubMed 
circadian rhythm IEP
Inferred from Expression Pattern
more info
PubMed 
negative regulation of protein binding IEA
Inferred from Electronic Annotation
more info
 
negative regulation of protein binding ISO
Inferred from Sequence Orthology
more info
PubMed 
postsynaptic actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
postsynaptic actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of cyclin-dependent protein serine/threonine kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of norepinephrine uptake IEA
Inferred from Electronic Annotation
more info
 
regulation of norepinephrine uptake IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of norepinephrine uptake IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of norepinephrine uptake ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
 
regulation of protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
regulation of transmembrane transporter activity IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
PubMed 
response to immobilization stress IEP
Inferred from Expression Pattern
more info
PubMed 
response to mechanical stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
retina development in camera-type eye IEP
Inferred from Expression Pattern
more info
PubMed 
synaptic vesicle endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic vesicle endocytosis IEA
Inferred from Electronic Annotation
more info
 
synaptic vesicle endocytosis ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
NuA4 histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NuA4 histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
 
NuA4 histone acetyltransferase complex ISO
Inferred from Sequence Orthology
more info
PubMed 
Schaffer collateral - CA1 synapse IEA
Inferred from Electronic Annotation
more info
 
Schaffer collateral - CA1 synapse ISO
Inferred from Sequence Orthology
more info
PubMed 
actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
PubMed 
actin filament IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
axon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
axon IDA
Inferred from Direct Assay
more info
PubMed 
calyx of Held IEA
Inferred from Electronic Annotation
more info
 
calyx of Held ISO
Inferred from Sequence Orthology
more info
PubMed 
cortical cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cortical cytoskeleton ISO
Inferred from Sequence Orthology
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
cytoplasmic ribonucleoprotein granule IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic ribonucleoprotein granule ISO
Inferred from Sequence Orthology
more info
PubMed 
cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
cytoskeleton ISO
Inferred from Sequence Orthology
more info
PubMed 
cytoskeleton ISS
Inferred from Sequence or Structural Similarity
more info
 
cytosol IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
dense body ISS
Inferred from Sequence or Structural Similarity
more info
 
focal adhesion ISS
Inferred from Sequence or Structural Similarity
more info
 
glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 
glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
PubMed 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
podosome IDA
Inferred from Direct Assay
more info
PubMed 
postsynaptic actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
postsynaptic actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
PubMed 
postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
presynapse IEA
Inferred from Electronic Annotation
more info
 
protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
PubMed 
ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
PubMed 
stress fiber IDA
Inferred from Direct Assay
more info
PubMed 
synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
actin, cytoplasmic 1
Names
beta-actin
cytoplasmic beta-actin

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031144.3NP_112406.1  actin, cytoplasmic 1

    See identical proteins and their annotated locations for NP_112406.1

    Status: PROVISIONAL

    Source sequence(s)
    BC063166
    UniProtKB/Swiss-Prot
    P60711
    Related
    ENSRNOP00000044296.2, ENSRNOT00000042459.4
    Conserved Domains (1) summary
    PTZ00281
    Location:1375
    PTZ00281; actin; Provisional

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005111.4 Reference Rnor_6.0 Primary Assembly

    Range
    13715843..13718813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000080.1 Alternate Rn_Celera

    Range
    13452443..13455413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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