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CYP71A12 cytochrome P450 family 71 polypeptide [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817626, updated on 19-Nov-2025
Official Symbol
CYP71A12
Official Full Name
cytochrome P450 family 71 polypeptide
Primary source
TAIR:AT2G30750
Locus tag
AT2G30750
See related
Araport:AT2G30750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
cytochrome P450; family 71; polypeptide 12; subfamily A; T11J7.14; T11J7_14
Summary
putative cytochrome P450
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See CYP71A12 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
4
Sequence:
Chromosome: 2; NC_003071.7 (13099486..13101371, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene Protein kinase superfamily protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene cytochrome P450 family 71 polypeptide

Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The role of CYP71A12 monooxygenase in pathogen-triggered tryptophan metabolism and Arabidopsis immunity. Pastorczyk M, et al. New Phytol, 2020 Jan. PMID 31411742
  2. TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASE-Mediated Generation and Metabolic Analysis of Camalexin-Deficient cyp71a12 cyp71a13 Double Knockout Lines. Müller TM, et al. Plant Physiol, 2015 Jul. PMID 25953104, Free PMC Article
  3. The Formation of a Camalexin Biosynthetic Metabolon. Mucha S, et al. Plant Cell, 2019 Nov. PMID 31511315, Free PMC Article
  4. Arabidopsis cytochrome P450 monooxygenase 71A13 catalyzes the conversion of indole-3-acetaldoxime in camalexin synthesis. Nafisi M, et al. Plant Cell, 2007 Jun. PMID 17573535, Free PMC Article
  5. Metabolic and transcriptomic changes induced in Arabidopsis by the rhizobacterium Pseudomonas fluorescens SS101. van de Mortel JE, et al. Plant Physiol, 2012 Dec. PMID 23073694, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The role of CYP71A12 monooxygenase in pathogen-triggered tryptophan metabolism and Arabidopsis immunity.
    Title: The role of CYP71A12 monooxygenase in pathogen-triggered tryptophan metabolism and Arabidopsis immunity.
  2. In contrast to cyp71a13 plants, in which camalexin accumulation is partially reduced, double mutants synthesized only traces of camalexin, demonstrating that CYP71A12 contributes to camalexin biosynthesis in leaf tissue.
    Title: TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASE-Mediated Generation and Metabolic Analysis of Camalexin-Deficient cyp71a12 cyp71a13 Double Knockout Lines.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

NM_128628.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within defense response to bacterium IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within induced systemic resistance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to bacterium IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum lumen IDA
Inferred from Direct Assay
more info
  
Preferred Names
cytochrome P450 family 71 polypeptide
NP_180633.3
  • cytochrome P450, family 71, subfamily A, polypeptide 12 (CYP71A12); FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding; INVOLVED IN: response to bacterium; LOCATED IN: endomembrane system; EXPRESSED IN: stem, stamen; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 71, subfamily A, polypeptide 13 (TAIR:AT2G30770.1); Has 34196 Blast hits to 33993 proteins in 1718 species: Archae - 48; Bacteria - 4046; Metazoa - 11921; Fungi - 7292; Plants - 9674; Viruses - 3; Other Eukaryotes - 1212 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    13099486..13101371 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128628.4 → NP_180633.3  cytochrome P450 family 71 polypeptide [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4INX7, O49340, Q8LPP9
    UniProtKB/TrEMBL
    A0A178VN27, A0A5S9X2U8, A0A654EXK9
    Conserved Domains (1) summary
    cd11072
    Location:63 → 489
    CYP71-like; cytochrome P450 family 71 and similar cytochrome P450s
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O49340.1

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