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TPP thylakoid processing peptide [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817595, updated on 15-Oct-2023

Summary

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Gene symbol
TPP
Gene description
thylakoid processing peptide
Primary source
Araport:AT2G30440
Locus tag
AT2G30440
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
plastidic type I signal peptidase 2B; Plsp2B; T6B20.20; T6B20_20; thylakoid processing peptide
Summary
Encodes a thylakoidal processing peptidase that removes signal sequences from proteins synthesized in the cytoplasm and transported into the thylakoid lumen.
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Genomic context

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Location:
chromosome: 2
Exon count:
6
Sequence:
Chromosome: 2; NC_003071.7 (12972682..12975542)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Homeodomain-like superfamily protein Neighboring gene ncRNA Neighboring gene tRNA-Gly

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional diversification of thylakoidal processing peptidases in Arabidopsis thaliana. Hsu SC, et al. PLoS One, 2011. PMID 22087276, Free PMC Article
  2. Characterization of a cDNA encoding the thylakoidal processing peptidase from Arabidopsis thaliana. Implications for the origin and catalytic mechanism of the enzyme. Chaal BK, et al. J Biol Chem, 1998 Jan 9. PMID 9422718
  3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

NM_128597.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables endopeptidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within signal peptide processing IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast thylakoid IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
thylakoid processing peptide
NP_180603.2
  • thylakoid processing peptide (TPP); CONTAINS InterPro DOMAIN/s: Peptidase S24/S26A/S26B/S26C, beta-ribbon domain (InterPro:IPR011056), Peptidase S24/S26A/S26B/S26C (InterPro:IPR015927), Peptidase S26A, signal peptidase I, conserved site (InterPro:IPR019758), Peptidase S26, conserved region (InterPro:IPR019533), Peptidase S26A, signal peptidase I (InterPro:IPR000223), Peptidase S26A, signal peptidase I, serine active site (InterPro:IPR019756); BEST Arabidopsis thaliana protein match is: Peptidase S24/S26A/S26B/S26C family protein (TAIR:AT1G06870.1); Has 9797 Blast hits to 9593 proteins in 2427 species: Archae - 0; Bacteria - 7318; Metazoa - 215; Fungi - 115; Plants - 235; Viruses - 0; Other Eukaryotes - 1914 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    12972682..12975542
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128597.3 → NP_180603.2  thylakoid processing peptide [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180603.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O04348, Q7DM64
    UniProtKB/TrEMBL
    A0A178VYT7, A0A5S9X2R9, A0A654F2L8
    Conserved Domains (1) summary
    pfam10502
    Location:157 → 317
    Peptidase_S26; Signal peptidase, peptidase S26
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O04348.2

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