Format

Send to:

Choose Destination

CPN60A chaperonin-60alpha [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817344, updated on 12-Aug-2018

Summary

Gene symbol
CPN60A
Gene description
chaperonin-60alpha
Primary source
Araport:AT2G28000
Locus tag
AT2G28000
Gene type
protein coding
RNA name
chaperonin-60alpha
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CH-CPN60A; chaperonin-60alpha; CHAPERONIN-60ALPHA; chaperonin-60alpha1; CHLOROPLAST CHAPERONIN 60ALPHA; Cpn60alpha1; SCHLEPPERLESS; SLP; T1E2.8; T1E2_8
Summary
Encodes chaperonin-60 alpha, a molecular chaperone involved in Rubisco folding. Mutants display aberrant chloroplast and embryo development.

Genomic context

See CPN60A in Genome Data Viewer
Location:
chromosome: 2
Exon count:
8
Sequence:
Chromosome: 2; NC_003071.7 (11926446..11929488)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger domain-containing protein Neighboring gene CDK-subunit 2 Neighboring gene BEL1-like homeodomain 8 Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene mediator of RNA polymerase II transcription subunit

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_128359.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
'de novo' protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chloroplast organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
embryo development ending in seed dormancy IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitochondrion organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein folding TAS
Traceable Author Statement
more info
PubMed 
protein refolding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
apoplast IDA
Inferred from Direct Assay
more info
PubMed 
chloroplast IDA
Inferred from Direct Assay
more info
PubMed 
chloroplast ISM
Inferred from Sequence Model
more info
 
chloroplast ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
chloroplast envelope IDA
Inferred from Direct Assay
more info
PubMed 
chloroplast stroma IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NOT cytosol RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
cytosolic ribosome IDA
Inferred from Direct Assay
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
thylakoid IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
chaperonin-60alpha
NP_180367.1
  • chaperonin-60alpha (CPN60A); FUNCTIONS IN: ATP binding; INVOLVED IN: protein folding, chloroplast organization, embryo development; LOCATED IN: in 8 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Chaperonin Cpn60/TCP-1 (InterPro:IPR002423), Chaperonin Cpn60, conserved site (InterPro:IPR018370), Chaperonin Cpn60 (InterPro:IPR001844); BEST Arabidopsis thaliana protein match is: TCP-1/cpn60 chaperonin family protein (TAIR:AT5G18820.1); Has 33896 Blast hits to 33887 proteins in 8716 species: Archae - 792; Bacteria - 21835; Metazoa - 1656; Fungi - 1573; Plants - 797; Viruses - 2; Other Eukaryotes - 7241 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    11926446..11929488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128359.5NP_180367.1  chaperonin-60alpha [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180367.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P21238
    UniProtKB/TrEMBL
    A0A178VZW6
    Conserved Domains (2) summary
    PRK12850
    Location:49569
    groEL; chaperonin GroEL; Reviewed
    cd03344
    Location:49569
    GroEL; GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found ...
Support Center