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AXS1 UDP-D-apiose/UDP-D-xylose synthase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817332, updated on 13-May-2026
Official Symbol
AXS1
Official Full Name
UDP-D-apiose/UDP-D-xylose synthase 1
Primary source
TAIR:AT2G27860
Locus tag
AT2G27860
See related
Araport:AT2G27860
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F15K20.4; F15K20_4; UDP-D-apiose/UDP-D-xylose synthase 1
Summary
Encodes UDP-d-apiose/UDP-d-xylose synthase that requires NAD+ for enzymatic activity and is strongly inhibited by UDP-d-galacturonate.
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See AXS1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
9
Sequence:
Chromosome: 2; NC_003071.7 (11864277..11866998, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene histone deacetylase-related / HD-like protein Neighboring gene tRNA-Gly Neighboring gene pseudo Neighboring gene Argonaute family protein

Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The biosynthesis of the branched-chain sugar d-apiose in plants: functional cloning and characterization of a UDP-d-apiose/UDP-d-xylose synthase from Arabidopsis. Mølhøj M, et al. Plant J, 2003 Sep. PMID 12969423
  2. Arabidopsis thaliana AHL family modulates hypocotyl growth redundantly by interacting with each other via the PPC/DUF296 domain. Zhao J, et al. Proc Natl Acad Sci U S A, 2013 Nov 26. PMID 24218605, Free PMC Article
  3. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
  4. Profiling of the Receptor for Activated C Kinase 1a (RACK1a) interaction network in Arabidopsis thaliana. Guo J, et al. Biochem Biophys Res Commun, 2019 Dec 3. PMID 31606202
  5. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description
NM_128345.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables NAD binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables UDP-D-apiose synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables UDP-D-apiose synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables UDP-D-apiose synthase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables UDP-glucuronate decarboxylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables UDP-glucuronate decarboxylase activity IEA
Inferred from Electronic Annotation
more info
  
enables carboxy-lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in UDP-D-apiose biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in UDP-D-apiose biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in UDP-D-apiose biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in UDP-D-xylose biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in UDP-D-xylose biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within nucleotide-sugar biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus ISM
Inferred from Sequence Model
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm NAS
Non-traceable Author Statement
more info
 PubMed 
located_in cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol HDA PubMed 
located_in peroxisome HDA PubMed 
Preferred Names
UDP-D-apiose/UDP-D-xylose synthase 1
NP_180353.1
  • UDP-D-apiose/UDP-D-xylose synthase 1 (AXS1); FUNCTIONS IN: NAD or NADH binding, UDP-glucuronate decarboxylase activity; INVOLVED IN: nucleotide-sugar biosynthetic process; LOCATED IN: cytoplasm; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, seed development stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: UDP-D-apiose/UDP-D-xylose synthase 2 (TAIR:AT1G08200.1); Has 19662 Blast hits to 19651 proteins in 2697 species: Archae - 540; Bacteria - 12327; Metazoa - 255; Fungi - 84; Plants - 1208; Viruses - 17; Other Eukaryotes - 5231 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    11864277..11866998 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128345.4 → NP_180353.1  UDP-D-apiose/UDP-D-xylose synthase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180353.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9ZUY6
    UniProtKB/TrEMBL
    A0A178VYU0, A0A5S9X1U0
    Conserved Domains (1) summary
    PLN02427
    Location:4 → 389
    PLN02427; UDP-apiose/xylose synthase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZUY6.1

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