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SCAB1 plectin-like protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817218, updated on 18-Sep-2024
Official Symbol
SCAB1
Official Full Name
plectin-like protein
Primary source
TAIR:AT2G26770
Locus tag
AT2G26770
See related
Araport:AT2G26770
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F18A8.14; F18A8_14; stomatal closure-related actin binding protein 1
Summary
Encodes a plant-specific actin binding protein SCAB1 (STOMATAL CLOSURE-RELATED ACTIN BINDING PROTEIN1). SCAB1 stabilizes actin filaments and regulates stomatal movement.
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See SCAB1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
14
Sequence:
Chromosome: 2; NC_003071.7 (11403979..11408421, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene Cyclin B1;4 Neighboring gene ncRNA Neighboring gene ARM repeat superfamily protein Neighboring gene ncRNA

Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. SCAB1 coordinates sequential Ca(2+) and ABA signals during osmotic stress induced stomatal closure in Arabidopsis. Zhang T, et al. Sci China Life Sci, 2024 Jan. PMID 38153680
  2. Phosphatidylinositol 3-phosphate regulates SCAB1-mediated F-actin reorganization during stomatal closure in Arabidopsis. Yang Y, et al. Plant Cell, 2022 Jan 20. PMID 34850207, Free PMC Article
  3. Plant actin-binding protein SCAB1 is dimeric actin cross-linker with atypical pleckstrin homology domain. Zhang W, et al. J Biol Chem, 2012 Apr 6. PMID 22356912, Free PMC Article
  4. The plant-specific actin binding protein SCAB1 stabilizes actin filaments and regulates stomatal movement in Arabidopsis. Zhao Y, et al. Plant Cell, 2011 Jun. PMID 21719691, Free PMC Article
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SCAB1 coordinates sequential Ca[2+] and ABA signals during osmotic stress induced stomatal closure in Arabidopsis.
    Title: SCAB1 coordinates sequential Ca(2+) and ABA signals during osmotic stress induced stomatal closure in Arabidopsis.
  2. Phosphatidylinositol 3-phosphate regulates SCAB1-mediated F-actin reorganization during stomatal closure in Arabidopsis.
    Title: Phosphatidylinositol 3-phosphate regulates SCAB1-mediated F-actin reorganization during stomatal closure in Arabidopsis.
  3. SCAB1 is a novel plant-specific actin-binding protein that binds, bundles, and stabilizes actin filaments and regulates stomatal movement. [SCAB1]
    Title: Plant actin-binding protein SCAB1 is dimeric actin cross-linker with atypical pleckstrin homology domain.
  4. SCAB1 is required for the precise regulation of actin filament reorganization during stomatal closure. [SCAB1]
    Title: The plant-specific actin binding protein SCAB1 stabilizes actin filaments and regulates stomatal movement in Arabidopsis.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description
NM_001336082.1
NM_128234.4
NM_179754.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables actin binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within actin filament organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of stomatal movement IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  
Preferred Names
plectin-like protein
NP_180245.1
  • plectin-related; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT2G40820.1); Has 4721 Blast hits to 4136 proteins in 536 species: Archae - 91; Bacteria - 672; Metazoa - 2162; Fungi - 328; Plants - 350; Viruses - 13; Other Eukaryotes - 1105 (source: NCBI BLink).
NP_850085.1
  • plectin-related; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT2G40820.1); Has 4722 Blast hits to 4137 proteins in 536 species: Archae - 91; Bacteria - 673; Metazoa - 2162; Fungi - 328; Plants - 350; Viruses - 13; Other Eukaryotes - 1105 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    11403979..11408421 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_179754.2 → NP_850085.1  plectin-like protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850085.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O48791
    UniProtKB/TrEMBL
    A0A178VYU3, A0A7G2EBD0
    Conserved Domains (4) summary
    pfam16711
    Location:55 → 95
    SCAB-ABD; Actin-binding domain of plant-specific actin-binding protein
    pfam16709
    Location:281 → 378
    SCAB-IgPH; Fused Ig-PH domain of plant-specific actin-binding protein
    pfam16712
    Location:100 → 267
    SCAB_CC; Coiled-coil regions of plant-specific actin-binding protein
    pfam17684
    Location:381 → 488
    SCAB-PH; PH domain of plant-specific actin-binding protein

  2. NM_128234.4 → NP_180245.1  plectin-like protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180245.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O48791
    UniProtKB/TrEMBL
    A0A178VYU3, A0A7G2EBD0
    Conserved Domains (4) summary
    pfam16711
    Location:55 → 95
    SCAB-ABD; Actin-binding domain of plant-specific actin-binding protein
    pfam16709
    Location:281 → 378
    SCAB-IgPH; Fused Ig-PH domain of plant-specific actin-binding protein
    pfam16712
    Location:100 → 267
    SCAB_CC; Coiled-coil regions of plant-specific actin-binding protein
    pfam17684
    Location:381 → 488
    SCAB-PH; PH domain of plant-specific actin-binding protein

  3. NM_001336082.1 → NP_001323795.1  plectin-like protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O48791
    UniProtKB/TrEMBL
    A0A178VYU3, A0A7G2EBD0
    Conserved Domains (4) summary
    pfam16711
    Location:55 → 95
    SCAB-ABD; Actin-binding domain of plant-specific actin-binding protein
    pfam16709
    Location:281 → 378
    SCAB-IgPH; Fused Ig-PH domain of plant-specific actin-binding protein
    pfam16712
    Location:100 → 267
    SCAB_CC; Coiled-coil regions of plant-specific actin-binding protein
    pfam17684
    Location:381 → 488
    SCAB-PH; PH domain of plant-specific actin-binding protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O48791.1

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