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SDR2 NAD(P)-binding Rossmann-fold superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816953, updated on 18-Sep-2024

Summary

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Official Symbol
SDR2
Official Full Name
NAD(P)-binding Rossmann-fold superfamily protein
Primary source
TAIR:AT2G24190
Locus tag
AT2G24190
See related
Araport:AT2G24190
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F27D4.10; F27D4_10; short-chain dehydrogenase/reductase 2
Summary
Encodes an aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on saturated and alpha,beta-unsaturated aldehydes with more than 5 carbons in vitro. In addition, this enzyme can reduce methylglyoxal in vitro. It is believed that this enzyme localizes to the cytosol like the closely related protein encoded by AT3G61220.
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Genomic context

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See SDR2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
5
Sequence:
Chromosome: 2; NC_003071.7 (10283621..10285098, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene Endomembrane protein 70 protein family Neighboring gene cytochrome p450 71b6 Neighboring gene uncharacterized protein Neighboring gene Cytosol aminopeptidase family protein Neighboring gene ECA1 gametogenesis related family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. NADPH-dependent reductases involved in the detoxification of reactive carbonyls in plants. Yamauchi Y, et al. J Biol Chem, 2011 Mar 4. PMID 21169366, Free PMC Article
  2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

NM_001084482.3
NM_127980.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables alcohol dehydrogenase (NADP+) activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
NAD(P)-binding Rossmann-fold superfamily protein
NP_001077951.1
  • NAD(P)-binding Rossmann-fold superfamily protein; FUNCTIONS IN: oxidoreductase activity, binding, catalytic activity; INVOLVED IN: oxidation reduction, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NAD(P)-binding domain (InterPro:IPR016040), Glucose/ribitol dehydrogenase (InterPro:IPR002347), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT3G61220.2); Has 72615 Blast hits to 72550 proteins in 3183 species: Archae - 711; Bacteria - 48651; Metazoa - 4595; Fungi - 3717; Plants - 2402; Viruses - 0; Other Eukaryotes - 12539 (source: NCBI BLink).
NP_179996.1
  • NAD(P)-binding Rossmann-fold superfamily protein; FUNCTIONS IN: oxidoreductase activity, binding, catalytic activity; INVOLVED IN: oxidation reduction, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NAD(P)-binding domain (InterPro:IPR016040), Glucose/ribitol dehydrogenase (InterPro:IPR002347), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT3G61220.1); Has 72712 Blast hits to 72647 proteins in 3171 species: Archae - 711; Bacteria - 48573; Metazoa - 4611; Fungi - 3797; Plants - 2398; Viruses - 0; Other Eukaryotes - 12622 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    10283621..10285098 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127980.4 → NP_179996.1  NAD(P)-binding Rossmann-fold superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179996.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8MRH1, Q9ZUH5
    UniProtKB/TrEMBL
    A0A654EVL3
    Conserved Domains (2) summary
    cd05324
    Location:7 → 296
    carb_red_PTCR-like_SDR_c; Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs
    pfam00106
    Location:9 → 256
    adh_short; short chain dehydrogenase

  2. NM_001084482.3 → NP_001077951.1  NAD(P)-binding Rossmann-fold superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001077951.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654EVL3
    Conserved Domains (2) summary
    cd05324
    Location:12 → 301
    carb_red_PTCR-like_SDR_c; Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs
    pfam00106
    Location:14 → 261
    adh_short; short chain dehydrogenase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZUH5.1

Gene LinkOut

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