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Gna11 G protein subunit alpha 11 [ Rattus norvegicus (Norway rat) ]

Gene ID: 81662, updated on 18-Sep-2018

Summary

Official Symbol
Gna11provided by RGD
Official Full Name
G protein subunit alpha 11provided by RGD
Primary source
RGD:619749
See related
Ensembl:ENSRNOG00000005446
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
may be involved in mediating second messenger signals from the endothelin receptor in adipocytes [RGD, Feb 2006]
Expression
Biased expression in Adrenal (RPKM 136.4), Kidney (RPKM 135.2) and 9 other tissues See more
Orthologs

Genomic context

See Gna11 in Genome Data Viewer
Location:
7q11
Exon count:
7
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11033400..11047284)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (11200712..11214475)

Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene transducin-like enhancer of split 2 Neighboring gene amino-terminal enhancer of split Neighboring gene G protein subunit alpha 15 Neighboring gene sphingosine-1-phosphate receptor 4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
G protein-coupled receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
 
G-protein beta/gamma-subunit complex binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G-protein beta/gamma-subunit complex binding IEA
Inferred from Electronic Annotation
more info
 
GTP binding IDA
Inferred from Direct Assay
more info
PubMed 
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
alkylglycerophosphoethanolamine phosphodiesterase activity IDA
Inferred from Direct Assay
more info
PubMed 
guanyl nucleotide binding TAS
Traceable Author Statement
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein-containing complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
type 2A serotonin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
type 2A serotonin receptor binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
G protein-coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
action potential IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
action potential IEA
Inferred from Electronic Annotation
more info
 
action potential ISO
Inferred from Sequence Orthology
more info
 
adenylate cyclase-modulating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to pH IEA
Inferred from Electronic Annotation
more info
 
cellular response to pH ISO
Inferred from Sequence Orthology
more info
 
developmental pigmentation IEA
Inferred from Electronic Annotation
more info
 
developmental pigmentation ISO
Inferred from Sequence Orthology
more info
 
NOT glutamate receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
heart development IEA
Inferred from Electronic Annotation
more info
 
heart development ISO
Inferred from Sequence Orthology
more info
 
phospholipase C-activating dopamine receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phospholipase C-activating dopamine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
phospholipase C-activating dopamine receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
protein heterotrimerization IDA
Inferred from Direct Assay
more info
PubMed 
regulation of melanocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
regulation of melanocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
skeletal system development IEA
Inferred from Electronic Annotation
more info
 
skeletal system development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
guanine nucleotide-binding protein subunit alpha-11
Names
g alpha-11
guanine nucleotide binding protein, alpha 11
guanine nucleotide regulatory protein G alpha 11
guanine nucleotide-binding protein alpha 11 subunit

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031033.1NP_112295.1  guanine nucleotide-binding protein subunit alpha-11

    See identical proteins and their annotated locations for NP_112295.1

    Status: PROVISIONAL

    Source sequence(s)
    AF239674
    UniProtKB/Swiss-Prot
    Q9JID2
    Related
    ENSRNOP00000007498.3, ENSRNOT00000007498.4
    Conserved Domains (2) summary
    cd00066
    Location:40353
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
    smart00275
    Location:19357
    G_alpha; G protein alpha subunit

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

    Range
    11033400..11047284
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000075.1 Alternate Rn_Celera

    Range
    6354654..6368340
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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