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PRF1 profilin 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816495, updated on 18-Sep-2024
Official Symbol
PRF1
Official Full Name
profilin 1
Primary source
TAIR:AT2G19760
Locus tag
AT2G19760
See related
Araport:AT2G19760
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F6F22.21; F6F22_21; PFN1; profilin 1; PROFILIN 1
Summary
first member of the Arabidopsis profilin multigene family, expressed in all organs of Arabidopsis. Binds poly-L-proline. The first intron of PRF1 enhances gene expression in vegetative tissues.
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See PRF1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Sequence:
Chromosome: 2; NC_003071.7 (8516658..8518194, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Ribosomal protein S30 family protein Neighboring gene pseudo Neighboring gene profilin 5 Neighboring gene Leucine-rich repeat (LRR) family protein

Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Profilin-Dependent Nucleation and Assembly of Actin Filaments Controls Cell Elongation in Arabidopsis. Cao L, et al. Plant Physiol, 2016 Jan. PMID 26574597, Free PMC Article
  2. Small changes in the regulation of one Arabidopsis profilin isovariant, PRF1, alter seedling development. McKinney EC, et al. Plant Cell, 2001 May. PMID 11340190, Free PMC Article
  3. Arabidopsis profilin isoforms, PRF1 and PRF2 show distinctive binding activities and subcellular distributions. Wang F, et al. J Integr Plant Biol, 2009 Feb. PMID 19200149
  4. Role of nucleotide exchange and hydrolysis in the function of profilin in action assembly. Perelroizen I, et al. J Biol Chem, 1996 May 24. PMID 8647830
  5. Arabidopsis plants deficient in constitutive class profilins reveal independent and quantitative genetic effects. Müssar KJ, et al. BMC Plant Biol, 2015 Jul 11. PMID 26160044, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PRF1 coordinates the stochastic dynamic properties of actin filaments by modulating formin-mediated actin nucleation and assembly during plant cell expansion.
    Title: Profilin-Dependent Nucleation and Assembly of Actin Filaments Controls Cell Elongation in Arabidopsis.
  2. formed a filamentous network likely associated with actin filaments
    Title: Arabidopsis profilin isoforms, PRF1 and PRF2 show distinctive binding activities and subcellular distributions.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

NM_127534.3

Gene Ontology Provided by TAIR

Process Evidence Code Pubs
acts_upstream_of_or_within actin polymerization or depolymerization IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within inflorescence development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within lateral root development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within leaf development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within unidimensional cell growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytoplasm TAS
Traceable Author Statement
more info
 PubMed 
located_in cytosol HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in nucleolus HDA PubMed 
located_in nucleus HDA PubMed 
located_in phragmoplast HDA PubMed 
located_in plant-type cell wall HDA PubMed 
located_in plasma membrane HDA PubMed 
located_in plasmodesma HDA PubMed 
located_in spindle HDA PubMed 
Preferred Names
profilin 1
NP_179566.1
  • profilin 1 (PRF1); FUNCTIONS IN: actin binding; INVOLVED IN: actin polymerization or depolymerization, cytoskeleton organization, unidimensional cell growth; LOCATED IN: in 8 components; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Profilin/allergen (InterPro:IPR002097), Profilin, plant (InterPro:IPR005455); BEST Arabidopsis thaliana protein match is: profilin 2 (TAIR:AT4G29350.1); Has 937 Blast hits to 936 proteins in 250 species: Archae - 0; Bacteria - 2; Metazoa - 144; Fungi - 125; Plants - 584; Viruses - 0; Other Eukaryotes - 82 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    8516658..8518194 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127534.3 → NP_179566.1  profilin 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179566.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q42449
    UniProtKB/TrEMBL
    A0A178VSE7, A0A5S9WZP5, A0A654EZD9
    Conserved Domains (1) summary
    pfam00235
    Location:1 → 128
    Profilin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q42449.1

Gene LinkOut

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