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ANKRD13C ankyrin repeat domain 13C [ Homo sapiens (human) ]

Gene ID: 81573, updated on 1-Jun-2020

Summary

Official Symbol
ANKRD13Cprovided by HGNC
Official Full Name
ankyrin repeat domain 13Cprovided by HGNC
Primary source
HGNC:HGNC:25374
See related
Ensembl:ENSG00000118454 MIM:615125
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
dJ677H15.3
Expression
Ubiquitous expression in brain (RPKM 5.7), endometrium (RPKM 4.8) and 25 other tissues See more
Orthologs

Genomic context

See ANKRD13C in Genome Data Viewer
Location:
1p31.1
Exon count:
16
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (70258999..70354977, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (70724685..70820471, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 40 Neighboring gene RNA, 7SL, cytoplasmic 242, pseudogene Neighboring gene serine and arginine rich splicing factor 11 Neighboring gene HHLA3 antisense RNA 1 Neighboring gene HERV-H LTR-associating 3 Neighboring gene cystathionine gamma-lyase

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
integrase gag-pol Analysis of HIV-1 proviral integration sites in antiretroviral treatment patients indicates that ANKRD13C gene favors HIV-1 integration for expansion and persistence of infected cells, suggesting HIV-1 IN interacts with ANKRD13C PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14998, DKFZp566D1346

Gene Ontology Provided by GOA

Function Evidence Code Pubs
signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
signaling receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
protein retention in ER lumen IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein retention in ER lumen IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of anoikis IDA
Inferred from Direct Assay
more info
PubMed 
regulation of receptor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of receptor biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 
colocalizes_with endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ankyrin repeat domain-containing protein 13C

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030816.5NP_110443.3  ankyrin repeat domain-containing protein 13C

    See identical proteins and their annotated locations for NP_110443.3

    Status: VALIDATED

    Source sequence(s)
    AL136717, AL353771, BC028840, BU622247, CD000035, CK299538
    Consensus CDS
    CCDS648.2
    UniProtKB/Swiss-Prot
    Q8N6S4
    Related
    ENSP00000359982.4, ENST00000370944.9
    Conserved Domains (5) summary
    cd00204
    Location:113199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam11904
    Location:259532
    GPCR_chapero_1; GPCR-chaperone
    pfam12796
    Location:148223
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:115164
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:115141
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    70258999..70354977 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005271234.3XP_005271291.1  ankyrin repeat domain-containing protein 13C isoform X2

    Conserved Domains (5) summary
    cd00204
    Location:113199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam11904
    Location:259464
    GPCR_chapero_1; GPCR-chaperone
    pfam12796
    Location:148223
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:115164
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:115141
    ANK; ANK repeat [structural motif]
  2. XM_017002413.2XP_016857902.1  ankyrin repeat domain-containing protein 13C isoform X4

  3. XM_017002416.1XP_016857905.1  ankyrin repeat domain-containing protein 13C isoform X5

    Conserved Domains (1) summary
    pfam11904
    Location:1263
    GPCR_chapero_1; GPCR-chaperone
  4. XM_006710929.3XP_006710992.1  ankyrin repeat domain-containing protein 13C isoform X1

    Related
    ENSP00000262346.6, ENST00000262346.6
    Conserved Domains (5) summary
    cd00204
    Location:113199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam11904
    Location:259498
    GPCR_chapero_1; GPCR-chaperone
    pfam12796
    Location:148223
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:115164
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:115141
    ANK; ANK repeat [structural motif]
  5. XM_005271235.3XP_005271292.1  ankyrin repeat domain-containing protein 13C isoform X3

    Conserved Domains (5) summary
    cd00204
    Location:113199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam11904
    Location:259426
    GPCR_chapero_1; GPCR-chaperone
    pfam12796
    Location:148223
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:115164
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:115141
    ANK; ANK repeat [structural motif]
  6. XM_017002414.1XP_016857903.1  ankyrin repeat domain-containing protein 13C isoform X5

    Conserved Domains (1) summary
    pfam11904
    Location:1263
    GPCR_chapero_1; GPCR-chaperone
  7. XM_017002415.1XP_016857904.1  ankyrin repeat domain-containing protein 13C isoform X5

    Conserved Domains (1) summary
    pfam11904
    Location:1263
    GPCR_chapero_1; GPCR-chaperone

RNA

  1. XR_001737449.1 RNA Sequence

  2. XR_001737448.1 RNA Sequence

  3. XR_001737447.1 RNA Sequence

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