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YIPF5 Yip1 domain family member 5 [ Homo sapiens (human) ]

Gene ID: 81555, updated on 10-Oct-2020

Summary

Official Symbol
YIPF5provided by HGNC
Official Full Name
Yip1 domain family member 5provided by HGNC
Primary source
HGNC:HGNC:24877
See related
Ensembl:ENSG00000145817 MIM:611483
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SB140; SMAP5; YIP1A; SMAP-5; FinGER5
Expression
Ubiquitous expression in placenta (RPKM 14.2), thyroid (RPKM 12.3) and 25 other tissues See more
Orthologs

Genomic context

See YIPF5 in Genome Data Viewer
Location:
5q31.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (144158162..144170659, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (143537723..143550278, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene histocompatibility minor HB-1 Neighboring gene RNA, 7SL, cytoplasmic 87, pseudogene Neighboring gene potassium channel tetramerization domain containing 16 Neighboring gene CDC28 protein kinase regulatory subunit 1B pseudogene 5 Neighboring gene 60S ribosomal protein L9 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp313L2216

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
protein transport IEA
Inferred from Electronic Annotation
more info
 
regulation of ER to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
COPII-coated ER to Golgi transport vesicle IEA
Inferred from Electronic Annotation
more info
 
Golgi apparatus IDA
Inferred from Direct Assay
more info
 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 
endoplasmic reticulum exit site IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
protein YIPF5
Names
YIP1 family member 5
YPT-interacting protein 1 A
five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5
golgi membrane protein SB140
smooth muscle cell associated protein 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024947.4NP_001020118.1  protein YIPF5 isoform a

    See identical proteins and their annotated locations for NP_001020118.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 encode the same protein (isoform a).
    Source sequence(s)
    AY640926, AY640928, BP310538
    Consensus CDS
    CCDS4279.1
    UniProtKB/Swiss-Prot
    Q969M3
    Related
    ENSP00000397704.2, ENST00000448443.6
    Conserved Domains (1) summary
    cl21557
    Location:89257
    Yip1; Yip1 domain
  2. NM_001271732.2NP_001258661.1  protein YIPF5 isoform b

    See identical proteins and their annotated locations for NP_001258661.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate exon in the 5' coding region and uses a downstream start codon, compared to variant 1. It encodes isoform b which has a shorter N-terminus compared to isoform a.
    Source sequence(s)
    AY640926, AY640929, BP310538
    Consensus CDS
    CCDS64277.1
    UniProtKB/Swiss-Prot
    Q969M3
    Related
    ENSP00000425422.1, ENST00000513112.5
    Conserved Domains (1) summary
    cl21557
    Location:35203
    Yip1; Yip1 domain
  3. NM_030799.9NP_110426.4  protein YIPF5 isoform a

    See identical proteins and their annotated locations for NP_110426.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein (isoform a).
    Source sequence(s)
    AY640926, BP310538
    Consensus CDS
    CCDS4279.1
    UniProtKB/Swiss-Prot
    Q969M3
    Related
    ENSP00000274496.5, ENST00000274496.10
    Conserved Domains (1) summary
    cl21557
    Location:89257
    Yip1; Yip1 domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    144158162..144170659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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