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SPP signal peptide peptidase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 814841, updated on 27-Sep-2019

Summary

Gene symbol
SPP
Gene description
signal peptide peptidase
Primary source
Araport:AT2G03120
Locus tag
AT2G03120
Gene type
protein coding
RNA name
signal peptide peptidase
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATSPP; signal peptide peptidase; T18E12.21; T18E12_21
Summary
homologous to Signal Peptide Peptidases (SPP), required for pollen development and pollen germination. No homozygotes could be recovered from a T-DNA insertion mutant.

Genomic context

See SPP in Genome Data Viewer
Location:
chromosome: 2
Exon count:
11
Sequence:
Chromosome: 2; NC_003071.7 (937383..940551)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene putative RNA-binding protein Neighboring gene Ribosomal protein L12/ ATP-dependent Clp protease adaptor protein ClpS family protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_126363.7

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
aspartic endopeptidase activity, intramembrane cleaving IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
membrane protein proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
pollen development IMP
Inferred from Mutant Phenotype
more info
PubMed 
pollen germination IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal peptide processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
NOT Golgi apparatus RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of cytoplasmic side of endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of lumenal side of endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
signal peptide peptidase
NP_565294.1
  • signal peptide peptidase (SPP); FUNCTIONS IN: aspartic-type endopeptidase activity; INVOLVED IN: pollen germination, pollen development; LOCATED IN: endoplasmic reticulum, endoplasmic reticulum membrane; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22B, signal peptide peptidase (InterPro:IPR007369); BEST Arabidopsis thaliana protein match is: SIGNAL PEPTIDE PEPTIDASE-LIKE 1 (TAIR:AT4G33410.1); Has 989 Blast hits to 959 proteins in 196 species: Archae - 4; Bacteria - 0; Metazoa - 468; Fungi - 136; Plants - 243; Viruses - 0; Other Eukaryotes - 138 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    937383..940551
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_126363.7NP_565294.1  signal peptide peptidase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565294.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O81062
    UniProtKB/TrEMBL
    A0A178VY21
    Conserved Domains (1) summary
    pfam04258
    Location:47323
    Peptidase_A22B; Signal peptide peptidase
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