U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OR2T7 olfactory receptor family 2 subfamily T member 7 [ Homo sapiens (human) ]

Gene ID: 81458, updated on 26-Nov-2022

Summary

Official Symbol
OR2T7provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily T member 7provided by HGNC
Primary source
HGNC:HGNC:15019
See related
Ensembl:ENSG00000227152 AllianceGenome:HGNC:15019
Gene type
protein coding
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR2T7P; OST723
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Annotation information
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR2T7 in Genome Data Viewer
Location:
1q44
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (248436359..248444316)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (247880982..247888943)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248599660..248607617)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily T member 6 Neighboring gene olfactory receptor family 2 subfamily T member 1 Neighboring gene olfactory receptor family 2 subfamily T member 2 Neighboring gene uncharacterized LOC105373279 Neighboring gene olfactory receptor family 2 subfamily T member 3

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 2T7
Names
olfactory receptor OR1-44
olfactory receptor, family 2, subfamily T, member 7 pseudogene

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386051.2NP_001372980.2  olfactory receptor 2T7 isoform 1

    Status: INFERRED

    Description
    Transcript Variant: This variant (1, coding) represents the protein-coding allele encoded by the T2T-CHM13v2.0 genome assembly.
    Source sequence(s)
    CP068277
    Conserved Domains (1) summary
    cd15421
    Location:26301
    7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. NR_172522.1 RNA Sequence

    Status: INFERRED

    Description
    Transcript Variant: This variant (1, non-coding) uses the same exon combination as variant 1, coding, but represents the allele encoded by the GRCh38 reference assembly. This variant is represented as non-coding because a frameshift in the N-terminus results in a premature stop codon.
    Source sequence(s)
    AC138089

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    248436359..248444316
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791755.1 Reference GRCh38.p14 PATCHES

    Range
    84333..92290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187518.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    90399..98356
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_187646.1 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    86777..94734
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    247880982..247888943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_004272.4: Suppressed sequence

    Description
    NG_004272.4: This RefSeq was removed because it is now thought that this locus is a transcribed gene.
  2. NM_001355223.1: Suppressed sequence

    Description
    NM_001355223.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
  3. NM_001386052.1: Suppressed sequence

    Description
    NM_001386052.1: This RefSeq was removed because it is now thought that this gene is a pseudogene on the reference assembly GRCh38.