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OR4A8 olfactory receptor family 4 subfamily A member 8 (gene/pseudogene) [ Homo sapiens (human) ]

Gene ID: 81315, updated on 22-Sep-2022

Summary

Official Symbol
OR4A8provided by HGNC
Official Full Name
olfactory receptor family 4 subfamily A member 8 (gene/pseudogene)provided by HGNC
Primary source
HGNC:HGNC:15165
See related
Ensembl:ENSG00000225997 AllianceGenome:HGNC:15165
Gene type
pseudo
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR4A8P
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]
Annotation information
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
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Genomic context

See OR4A8 in Genome Data Viewer
Location:
11q11
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (54682876..54683820)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (54618901..54619845)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (51435460..51436404, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily A member 3 pseudogene Neighboring gene olfactory receptor family 4 subfamily A member 2 pseudogene Neighboring gene olfactory receptor family 4 subfamily A member 7 pseudogene Neighboring gene olfactory receptor family 4 subfamily A member 5

Genomic regions, transcripts, and products

General gene information

Other Names

  • Olfactory receptor 4A8
  • olfactory receptor, family 4, subfamily A, member 8 pseudogene

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_004235.3 

    Range
    101..1045
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    54682876..54683820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    54618901..54619845
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)