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OR51E2 olfactory receptor family 51 subfamily E member 2 [ Homo sapiens (human) ]

Gene ID: 81285, updated on 5-Jan-2022

Summary

Official Symbol
OR51E2provided by HGNC
Official Full Name
olfactory receptor family 51 subfamily E member 2provided by HGNC
Primary source
HGNC:HGNC:15195
See related
Ensembl:ENSG00000167332 MIM:611268
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PSGR; HPRAJ; OR52A2; OR51E3P
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Biased expression in prostate (RPKM 29.8) and placenta (RPKM 2.3) See more
Orthologs
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Genomic context

See OR51E2 in Genome Data Viewer
Location:
11p15.4
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (4680171..4697853, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (4701401..4719083, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376528 Neighboring gene olfactory receptor family 51 subfamily A member 9 pseudogene Neighboring gene olfactory receptor family 51 subfamily C member 1 pseudogene Neighboring gene olfactory receptor family 51 subfamily F member 5 pseudogene Neighboring gene matrix metallopeptidase 26 Neighboring gene olfactory receptor family 51 subfamily C member 4 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables olfactory receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables signaling receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables steroid hormone receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in early endosome membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in intracellular organelle IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 51E2
Names
olfactory receptor OR11-16
olfactory receptor, family 51, subfamily E, member 3 pseudogene
olfactory receptor, family 52, subfamily A, member 2
prostate-specific G-protein coupled receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030774.4NP_110401.1  olfactory receptor 51E2

    See identical proteins and their annotated locations for NP_110401.1

    Status: VALIDATED

    Source sequence(s)
    AC090719, AK314051
    Consensus CDS
    CCDS7751.1
    UniProtKB/Swiss-Prot
    Q9H255
    UniProtKB/TrEMBL
    A0A126GVK0
    Related
    ENSP00000380153.3, ENST00000396950.4
    Conserved Domains (1) summary
    cd15222
    Location:24298
    7tmA_OR51-like; olfactory receptor family 51 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    4680171..4697853 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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