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OR4F17 olfactory receptor family 4 subfamily F member 17 [ Homo sapiens (human) ]

Gene ID: 81099, updated on 22-Sep-2022

Summary

Official Symbol
OR4F17provided by HGNC
Official Full Name
olfactory receptor family 4 subfamily F member 17provided by HGNC
Primary source
HGNC:HGNC:15381
See related
Ensembl:ENSG00000176695 AllianceGenome:HGNC:15381
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR4F5; OR4F18; OR4F19; OR4F11P
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
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Genomic context

See OR4F17 in Genome Data Viewer
Location:
19p13.3
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (107104..113156)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (58109..64470)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (107104..113156)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily G member 3 pseudogene Neighboring gene olfactory receptor family 4 subfamily G member 1 pseudogene Neighboring gene WBP1L pseudogene 11 Neighboring gene olfactory receptor family 4 subfamily F member 8 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 4F17
Names
olfactory receptor 4F11
olfactory receptor 4F18
olfactory receptor 4F19
olfactory receptor, family 4, subfamily F, member 11 pseudogene
olfactory receptor, family 4, subfamily F, member 19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005240.3NP_001005240.1  olfactory receptor 4F17

    See identical proteins and their annotated locations for NP_001005240.1

    Status: VALIDATED

    Source sequence(s)
    AC008977
    Consensus CDS
    CCDS32854.1
    UniProtKB/Swiss-Prot
    B2RNE8, Q8NGA8
    UniProtKB/TrEMBL
    A0A126GWN0
    Related
    ENSP00000467301.1, ENST00000585993.3
    Conserved Domains (2) summary
    pfam00001
    Location:34280
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:24294
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    107104..113156
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    58109..64470
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)