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Syt13 synaptotagmin XIII [ Mus musculus (house mouse) ]

Gene ID: 80976, updated on 9-May-2024

Summary

Official Symbol
Syt13provided by MGI
Official Full Name
synaptotagmin XIIIprovided by MGI
Primary source
MGI:MGI:1933945
See related
Ensembl:ENSMUSG00000027220 AllianceGenome:MGI:1933945
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1427; 5730409J20Rik
Summary
Predicted to enable several functions, including SNARE binding activity; calcium ion binding activity; and phospholipid binding activity. Acts upstream of or within vesicle-mediated transport. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human SYT13 (synaptotagmin 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cortex adult (RPKM 37.9), cerebellum adult (RPKM 29.6) and 11 other tissues See more
Orthologs
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Genomic context

See Syt13 in Genome Data Viewer
Location:
2 E1; 2 51.37 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (92745446..92786403)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (92915101..92956051)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 39880 Neighboring gene predicted gene, 32413 Neighboring gene predicted gene 13791 Neighboring gene STARR-seq mESC enhancer starr_05153 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:92786015-92786280 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:92786303-92786486 Neighboring gene PR domain containing 11 Neighboring gene RIKEN cDNA 4631405J19 gene Neighboring gene STARR-positive B cell enhancer ABC_E9521 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:92889256-92889439 Neighboring gene predicted gene, 54114 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:92972327-92972528 Neighboring gene STARR-seq mESC enhancer starr_05158 Neighboring gene RIKEN cDNA 1700055L01 gene Neighboring gene predicted gene, 32627

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (4)  1 citation

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium-dependent phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables clathrin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphatidylserine binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in calcium-ion regulated exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within vesicle-mediated transport IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
is_active_in exocytic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in transport vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
synaptotagmin-13
Names
sytXIII

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030725.5NP_109650.1  synaptotagmin-13

    See identical proteins and their annotated locations for NP_109650.1

    Status: VALIDATED

    Source sequence(s)
    AL713913, AL844903
    Consensus CDS
    CCDS16451.1
    UniProtKB/Swiss-Prot
    Q6ZPR2, Q8BRK6, Q9EQT6
    Related
    ENSMUSP00000028648.3, ENSMUST00000028648.3
    Conserved Domains (2) summary
    cd08407
    Location:288425
    C2B_Synaptotagmin-13; C2 domain second repeat present in Synaptotagmin 13
    cl14603
    Location:160277
    C2; C2 domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    92745446..92786403
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)