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Klrb1b killer cell lectin-like receptor subfamily B member 1B [ Mus musculus (house mouse) ]

Gene ID: 80782, updated on 26-Sep-2022

Summary

Official Symbol
Klrb1bprovided by MGI
Official Full Name
killer cell lectin-like receptor subfamily B member 1Bprovided by MGI
Primary source
MGI:MGI:107539
See related
Ensembl:ENSMUSG00000079298 AllianceGenome:MGI:107539
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ly55b; Ly55d; Klrb1d; Nkrp1b; Nkrp1d; ly-55b; ly-55d; NKR-P1B; NKR-P1D; Nkrp1-b
Summary
Enables identical protein binding activity and signaling receptor activity. Acts upstream of or within negative regulation of natural killer cell mediated cytotoxicity. Located in external side of plasma membrane. Is integral component of plasma membrane. Orthologous to human KLRB1 (killer cell lectin like receptor B1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

See Klrb1b in Genome Data Viewer
Location:
6 F3; 6 63.09 cM
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (128790669..128803278, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (128813706..128826315, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene killer cell lectin-like receptor subfamily B member 1C Neighboring gene predicted gene, 34755 Neighboring gene predicted gene, 44066 Neighboring gene cDNA sequence BC035044 Neighboring gene predicted gene, 34849

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

General gene information

Homology

Clone Names

  • MGC163757, MGC163759

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables signaling receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
killer cell lectin-like receptor subfamily B member 1B allele B
Names
CD161 antigen-like family member B
NKR-P1 34
inhibitory receptor NKR-P1B
killer cell lectin-like receptor subfamily B member 1D
lymphocyte antigen 55 complex, locus B
lymphocyte antigen 55 complex, locus D
lymphocyte antigen 55b
lymphocyte antigen 55d
natural killer cell receptor protein NKR-P1B
natural killer cell receptor-P1
natural killer cell surface protein NKR-P1B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001364615.1NP_001351544.1  killer cell lectin-like receptor subfamily B member 1B allele B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC102693, AK138766
    Consensus CDS
    CCDS90126.1
    UniProtKB/TrEMBL
    G3UZU5
    Related
    ENSMUSP00000134637.2, ENSMUST00000172887.8
    Conserved Domains (2) summary
    cl02432
    Location:94138
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl25419
    Location:43143
    PHA02642; C-type lectin-like protein; Provisional
  2. NM_030599.4NP_085102.4  killer cell lectin-like receptor subfamily B member 1B allele B isoform 1

    See identical proteins and their annotated locations for NP_085102.4

    Status: VALIDATED

    Source sequence(s)
    AC102693, AK030702, AK041228
    Consensus CDS
    CCDS39655.1
    UniProtKB/Swiss-Prot
    Q99JB4, Q99P32
    UniProtKB/TrEMBL
    A0A1U9W1A4
    Related
    ENSMUSP00000032472.5, ENSMUST00000032472.11
    Conserved Domains (1) summary
    cd03593
    Location:94212
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    128790669..128803278 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)