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TMEM177 transmembrane protein 177 [ Homo sapiens (human) ]

Gene ID: 80775, updated on 5-Sep-2021

Summary

Official Symbol
TMEM177provided by HGNC
Official Full Name
transmembrane protein 177provided by HGNC
Primary source
HGNC:HGNC:28143
See related
Ensembl:ENSG00000144120
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in duodenum (RPKM 5.2), kidney (RPKM 5.0) and 25 other tissues See more
Orthologs
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Genomic context

See TMEM177 in Genome Data Viewer
Location:
2q14.2
Exon count:
19
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (119679170..119723618)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (120436777..120481194)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs1941 Neighboring gene secretin receptor Neighboring gene SCTR antisense RNA 1 Neighboring gene cilia and flagella associated protein 221 Neighboring gene uncharacterized LOC101927764 Neighboring gene ribosomal protein L17 pseudogene 15 Neighboring gene Sharpr-MPRA regulatory region 5959 Neighboring gene protein tyrosine phosphatase non-receptor type 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ32751, MGC10993

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105198.2NP_001098668.1  transmembrane protein 177

    See identical proteins and their annotated locations for NP_001098668.1

    Status: VALIDATED

    Source sequence(s)
    AC069154
    Consensus CDS
    CCDS2128.1
    UniProtKB/Swiss-Prot
    Q53S58
    Related
    ENSP00000402661.1, ENST00000424086.5
    Conserved Domains (1) summary
    cl02872
    Location:221264
    DHQ_Fe-ADH; Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH)
  2. NM_001105199.2NP_001098669.1  transmembrane protein 177

    See identical proteins and their annotated locations for NP_001098669.1

    Status: VALIDATED

    Source sequence(s)
    AC069154
    Consensus CDS
    CCDS2128.1
    UniProtKB/Swiss-Prot
    Q53S58
    Related
    ENSP00000385966.1, ENST00000401466.5
    Conserved Domains (1) summary
    cl02872
    Location:221264
    DHQ_Fe-ADH; Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH)
  3. NM_030577.3NP_085054.2  transmembrane protein 177

    See identical proteins and their annotated locations for NP_085054.2

    Status: VALIDATED

    Source sequence(s)
    AC069154
    Consensus CDS
    CCDS2128.1
    UniProtKB/Swiss-Prot
    Q53S58
    Related
    ENSP00000272521.6, ENST00000272521.7
    Conserved Domains (1) summary
    cl02872
    Location:221264
    DHQ_Fe-ADH; Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH)

RNA

  1. NR_148341.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC069154, AK057313, HY262393

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    119679170..119723618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_002959349.1 RNA Sequence

  2. XR_002959347.1 RNA Sequence

  3. XR_002959346.1 RNA Sequence

  4. XR_002959348.1 RNA Sequence

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