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PRR3 proline rich 3 [ Homo sapiens (human) ]

Gene ID: 80742, updated on 11-Jun-2021

Summary

Official Symbol
PRR3provided by HGNC
Official Full Name
proline rich 3provided by HGNC
Primary source
HGNC:HGNC:21149
See related
Ensembl:ENSG00000204576
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CAT56
Expression
Ubiquitous expression in ovary (RPKM 9.9), brain (RPKM 7.4) and 25 other tissues See more
Orthologs
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Genomic context

See PRR3 in Genome Data Viewer
Location:
6p21.33
Exon count:
4
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (30556709..30563723)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (30524486..30531500)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene major histocompatibility complex, class I, E Neighboring gene long intergenic non-protein coding RNA 2569 Neighboring gene G protein nucleolar 1 (putative) Neighboring gene ABCF1 divergent transcript Neighboring gene ATP binding cassette subfamily F member 1 Neighboring gene microRNA 877 Neighboring gene protein phosphatase 1 regulatory subunit 10 Neighboring gene mitochondrial ribosomal protein S18B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC161733, MGC161735

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
proline-rich protein 3
Names
MHC class I region proline-rich protein CAT56
proline-rich polypeptide 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077497.3NP_001070965.1  proline-rich protein 3 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL662800
    Consensus CDS
    CCDS43441.1
    UniProtKB/TrEMBL
    B3KQA4
    Related
    ENSP00000365740.3, ENST00000376557.3
    Conserved Domains (1) summary
    pfam00642
    Location:136160
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
  2. NM_025263.4NP_079539.2  proline-rich protein 3 isoform a

    See identical proteins and their annotated locations for NP_079539.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a).
    Source sequence(s)
    AL662800
    Consensus CDS
    CCDS43440.1
    UniProtKB/Swiss-Prot
    P79522
    UniProtKB/TrEMBL
    Q96QB9
    Related
    ENSP00000365744.4, ENST00000376560.8
    Conserved Domains (1) summary
    pfam00642
    Location:157181
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    30556709..30563723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_2

Genomic

  1. NT_113891.3 Reference GRCh38.p13 ALT_REF_LOCI_2

    Range
    2036429..2043443
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_3

Genomic

  1. NT_167245.2 Reference GRCh38.p13 ALT_REF_LOCI_3

    Range
    1812533..1819547
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_4

Genomic

  1. NT_167246.2 Reference GRCh38.p13 ALT_REF_LOCI_4

    Range
    1866938..1873952
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_5

Genomic

  1. NT_167247.2 Reference GRCh38.p13 ALT_REF_LOCI_5

    Range
    1900755..1907769
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_6

Genomic

  1. NT_167248.2 Reference GRCh38.p13 ALT_REF_LOCI_6

    Range
    1811794..1818808
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_7

Genomic

  1. NT_167249.2 Reference GRCh38.p13 ALT_REF_LOCI_7

    Range
    1857464..1864478
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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