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Rnf227 ring finger protein 227 [ Mus musculus (house mouse) ]

Gene ID: 80515, updated on 10-Mar-2023

Summary

Official Symbol
Rnf227provided by MGI
Official Full Name
ring finger protein 227provided by MGI
Primary source
MGI:MGI:1915359
See related
Ensembl:ENSMUSG00000043419 AllianceGenome:MGI:1915359
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RNF21; Chd3os; MNCb-2875; 2310043C11Rik; A030009H04Rik
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Is expressed in brain and spinal cord. Orthologous to human RNF227 (ring finger protein 227). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 38.4), frontal lobe adult (RPKM 30.6) and 6 other tissues See more
Orthologs
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Genomic context

See Rnf227 in Genome Data Viewer
Location:
11; 11 B3
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (69231622..69233467)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (69340796..69342641)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex 1 Neighboring gene potassium voltage-gated channel, shaker-related subfamily, beta member 3 Neighboring gene chromodomain helicase DNA binding protein 3 Neighboring gene predicted gene, 22442 Neighboring gene predicted gene, 32483

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
RING finger protein 227
Names
Chd3 opposite strand transcript
chromodomain helicase DNA binding protein 3, opposite strand

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001413473.1NP_001400402.1  RING finger protein 227

    Status: VALIDATED

    Source sequence(s)
    AL645527
    UniProtKB/Swiss-Prot
    Q9JJ82
    UniProtKB/TrEMBL
    A0A8C6N2Q3

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    69231622..69233467
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_020591.1: Suppressed sequence

    Description
    NM_020591.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.