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Zbtb10 zinc finger and BTB domain containing 10 [ Rattus norvegicus (Norway rat) ]

Gene ID: 80338, updated on 6-Jul-2026
Official Symbol
Zbtb10provided by RGD
Official Full Name
zinc finger and BTB domain containing 10provided by RGD
Primary source
RGD:708377
See related
Ensembl:ENSRNOG00000061862 AllianceGenome:RGD:708377
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rinzf; ania-11
Summary
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in chromosome, telomeric region and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ZBTB10 (zinc finger and BTB domain containing 10). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Kidney (RPKM 77.6), Heart (RPKM 70.3) and 9 other tissues See more
Orthologs
all
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See Zbtb10 in Genome Data Viewer
Location:
2q23
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (94382670..94417308, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (92475254..92509892, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485606 Neighboring gene uncharacterized LOC120100770 Neighboring gene zinc finger protein 704 Neighboring gene uncharacterized LOC120100771 Neighboring gene high mobility group protein B1-like

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. RIN ZF, a novel zinc finger gene, encodes proteins that bind to the CACC element of the gastrin promoter. Tillotson LG. J Biol Chem, 1999 Mar 19. PMID 10075714
  2. A complex program of striatal gene expression induced by dopaminergic stimulation. Berke JD, et al. J Neurosci, 1998 Jul 15. PMID 9651213, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IC
Inferred by Curator
more info
  
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables telomeric repeat DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome, telomeric region ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
zinc finger and BTB domain-containing protein 10
Names
zinc finger protein RIN ZF

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024489.2 → NP_077815.2  zinc finger and BTB domain-containing protein 10

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A0G2K3H8, A0ABK0LL11
    Related
    ENSRNOP00000072643.2, ENSRNOT00000087598.3
    Conserved Domains (5) summary
    smart00597
    Location:240 → 307
    ZnF_TTF; zinc finger in transposases and transcription factors
    sd00017
    Location:745 → 765
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl38908
    Location:363 → 484
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    pfam13465
    Location:758 → 782
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:743 → 767
    zf-H2C2_5; C2H2-type zinc-finger domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    94382670..94417308 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039103200.2 → XP_038959128.1  zinc finger and BTB domain-containing protein 10 isoform X1

    UniProtKB/TrEMBL
    A0A0G2JY41, A0ABK0LL11
    Related
    ENSRNOP00000070510.2, ENSRNOT00000081553.3
    Conserved Domains (5) summary
    smart00597
    Location:240 → 307
    ZnF_TTF; zinc finger in transposases and transcription factors
    sd00017
    Location:716 → 736
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl38908
    Location:334 → 455
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    pfam13465
    Location:729 → 753
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:714 → 738
    zf-H2C2_5; C2H2-type zinc-finger domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9WTY8.1 GenPept UniProtKB/Swiss-Prot:Q9WTY8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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