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Gpr146 G protein-coupled receptor 146 [ Mus musculus (house mouse) ]

Gene ID: 80290, updated on 18-Apr-2019

Summary

Official Symbol
Gpr146provided by MGI
Official Full Name
G protein-coupled receptor 146provided by MGI
Primary source
MGI:MGI:1933113
See related
Ensembl:ENSMUSG00000044197
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PGR8; BC003323; D830046C22Rik
Expression
Broad expression in lung adult (RPKM 19.7), mammary gland adult (RPKM 13.5) and 22 other tissues See more
Orthologs

Genomic context

See Gpr146 in Genome Data Viewer
Location:
5; 5 G2
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (139376431..139396415)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (139856621..139872368)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 3110082I17 gene Neighboring gene cytochrome P450, family 2, subfamily w, polypeptide 1 Neighboring gene microRNA 339 Neighboring gene RIKEN cDNA C130050O18 gene Neighboring gene G protein-coupled estrogen receptor 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Pathways from BioSystems

  • GPCRs, Other, organism-specific biosystem (from WikiPathways)
    GPCRs, Other, organism-specific biosystemThis pathway was created using the GPCRDB (Horn et al., 1998), http://www.cmbi.kun.nl/7tm/. The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used ...
  • Odorant GPCRs, organism-specific biosystem (from WikiPathways)
    Odorant GPCRs, organism-specific biosystem
    Odorant GPCRs

General gene information

Homology

Clone Names

  • MGC7035, MGC182532, MGC182544

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
probable G-protein coupled receptor 146

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001038703.3NP_001033792.1  probable G-protein coupled receptor 146

    See identical proteins and their annotated locations for NP_001033792.1

    Status: VALIDATED

    Source sequence(s)
    AC140216
    Consensus CDS
    CCDS19809.1
    UniProtKB/Swiss-Prot
    Q99LE2
    Related
    ENSMUSP00000098083.2, ENSMUST00000100514.2
    Conserved Domains (1) summary
    cd14990
    Location:27305
    7tmA_GPR146; G protein-coupled receptor 146, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_001362206.1NP_001349135.1  probable G-protein coupled receptor 146

    Status: VALIDATED

    Source sequence(s)
    AC140216, AC161058
    Conserved Domains (1) summary
    cd14990
    Location:27305
    7tmA_GPR146; G protein-coupled receptor 146, member of the class A family of seven-transmembrane G protein-coupled receptors
  3. NM_030258.5NP_084534.2  probable G-protein coupled receptor 146

    See identical proteins and their annotated locations for NP_084534.2

    Status: VALIDATED

    Source sequence(s)
    AC161058, AK155876, BB738958
    Consensus CDS
    CCDS19809.1
    UniProtKB/Swiss-Prot
    Q99LE2
    Related
    ENSMUSP00000049707.7, ENSMUST00000051293.7
    Conserved Domains (1) summary
    cd14990
    Location:27305
    7tmA_GPR146; G protein-coupled receptor 146, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. NR_033147.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant is represented as non-coding because it lacks the open reading frame found in the other variants.
    Source sequence(s)
    AK086028, AK087317
    Related
    ENSMUST00000188655.1

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

    Range
    139376431..139396415
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
  2. NC_000071.6 Reference GRCm38.p4 C57BL/6J

    Range
    139377697..139380053
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006504774.2XP_006504837.1  probable G-protein coupled receptor 146 isoform X1

    UniProtKB/Swiss-Prot
    Q99LE2
    Conserved Domains (1) summary
    cd14990
    Location:27305
    7tmA_GPR146; G protein-coupled receptor 146, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_001784759.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_177097.3: Suppressed sequence

    Description
    NM_177097.3: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.
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