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SLC35F5 solute carrier family 35 member F5 [ Homo sapiens (human) ]

Gene ID: 80255, updated on 18-Aug-2020

Summary

Official Symbol
SLC35F5provided by HGNC
Official Full Name
solute carrier family 35 member F5provided by HGNC
Primary source
HGNC:HGNC:23617
See related
Ensembl:ENSG00000115084
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 12.0), adrenal (RPKM 11.9) and 25 other tissues See more
Orthologs

Genomic context

See SLC35F5 in Genome Data Viewer
Location:
2q14.1
Exon count:
20
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (113702677..113756642, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (114471354..114514400, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 744, pseudogene Neighboring gene ACR pseudogene 1 Neighboring gene microRNA 4782 Neighboring gene uncharacterized LOC105373570 Neighboring gene ACTR3 antisense RNA 1 Neighboring gene actin related protein 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ22004, FLJ36584

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
solute carrier family 35 member F5
Names
HCV NS5A-transactivated protein 3
hepatitis C virus NS5A-transactivated protein 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330314.2NP_001317243.1  solute carrier family 35 member F5 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3)
    Source sequence(s)
    AC017074
    Consensus CDS
    CCDS82503.1
    UniProtKB/TrEMBL
    B8ZZY4
    Related
    ENSP00000386754.1, ENST00000409106.5
    Conserved Domains (2) summary
    COG0697
    Location:239464
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
    pfam00892
    Location:323464
    EamA; EamA-like transporter family
  2. NM_001330315.2NP_001317244.1  solute carrier family 35 member F5 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4)
    Source sequence(s)
    AC017074
    Conserved Domains (2) summary
    COG0697
    Location:245483
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
    pfam00892
    Location:342483
    EamA; EamA-like transporter family
  3. NM_001330316.2NP_001317245.1  solute carrier family 35 member F5 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5)
    Source sequence(s)
    AC017074
  4. NM_001330317.2NP_001317246.1  solute carrier family 35 member F5 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and 5' coding region, lacks multiple 3' coding exons, and extends past a splice site used in the variant 1, resulting in a different 3' coding region and 3' UTR. The encoded isoform (5) has distinct N- and C-termini compared to isoform 1.
    Source sequence(s)
    AC017074, AK025657, BC050096
    Consensus CDS
    CCDS86878.1
    UniProtKB/Swiss-Prot
    Q8WV83
    UniProtKB/TrEMBL
    B8ZZV6
    Related
    ENSP00000386991.1, ENST00000409342.1
  5. NM_025181.5NP_079457.2  solute carrier family 35 member F5 isoform 1

    See identical proteins and their annotated locations for NP_079457.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AC017074, AY358620
    Consensus CDS
    CCDS2119.1
    UniProtKB/Swiss-Prot
    Q8WV83
    UniProtKB/TrEMBL
    A0A024RAD4
    Related
    ENSP00000245680.2, ENST00000245680.7
    Conserved Domains (1) summary
    COG0697
    Location:242470
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]

RNA

  1. NR_104470.3 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site at the 5' end and lacks a segment in the 3' region. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC017074, BC050096

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    113702677..113756642 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017005027.1XP_016860516.1  solute carrier family 35 member F5 isoform X1

    Conserved Domains (2) summary
    COG0697
    Location:245483
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
    pfam00892
    Location:342483
    EamA; EamA-like transporter family
  2. XM_011511923.2XP_011510225.1  solute carrier family 35 member F5 isoform X3

    Conserved Domains (2) summary
    COG0697
    Location:245483
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
    pfam00892
    Location:342483
    EamA; EamA-like transporter family
  3. XM_011511922.2XP_011510224.1  solute carrier family 35 member F5 isoform X2

    Conserved Domains (2) summary
    COG0697
    Location:239477
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
    pfam00892
    Location:336477
    EamA; EamA-like transporter family
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