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TASL TLR adaptor interacting with endolysosomal SLC15A4 [ Homo sapiens (human) ]

Gene ID: 80231, updated on 11-Jun-2021

Summary

Official Symbol
TASLprovided by HGNC
Official Full Name
TLR adaptor interacting with endolysosomal SLC15A4provided by HGNC
Primary source
HGNC:HGNC:25667
See related
Ensembl:ENSG00000120280 MIM:301049
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CXorf21
Expression
Broad expression in appendix (RPKM 6.3), bone marrow (RPKM 6.2) and 17 other tissues See more
Orthologs
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Genomic context

See TASL in Genome Data Viewer
Location:
Xp21.2
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (30558809..30577766, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (30576926..30595883, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene NR0B1 5' regulatory region Neighboring gene phospholipase C epsilon 1 pseudogene 1 Neighboring gene nuclear receptor subfamily 0 group B member 1 Neighboring gene CDC28 protein kinase regulatory subunit 1B pseudogene 6 Neighboring gene ferritin light chain pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11577

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in endolysosome membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
TLR adapter interacting with SLC15A4 on the lysosome
Names
5430427O19Rik
TLR adaptor interacting with SLC15A4 on the lysosome
protein CXorf21
uncharacterized protein CXorf21

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016375.1 RefSeqGene

    Range
    5151..24108
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_025159.3NP_079435.1  TLR adapter interacting with SLC15A4 on the lysosome

    See identical proteins and their annotated locations for NP_079435.1

    Status: VALIDATED

    Source sequence(s)
    AC005913, AK021639, BC020611, BX281759
    Consensus CDS
    CCDS14224.1
    UniProtKB/Swiss-Prot
    Q9HAI6
    Related
    ENSP00000368245.3, ENST00000378962.4
    Conserved Domains (1) summary
    pfam15133
    Location:1296
    DUF4569; Domain of unknown function (DUF4569)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    30558809..30577766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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