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PROSER1 proline and serine rich 1 [ Homo sapiens (human) ]

Gene ID: 80209, updated on 1-Jun-2020

Summary

Official Symbol
PROSER1provided by HGNC
Official Full Name
proline and serine rich 1provided by HGNC
Primary source
HGNC:HGNC:20291
See related
Ensembl:ENSG00000120685
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C13orf23
Summary
This gene encodes a conserved protein containing proline and serine rich regions. These regions may be important in protein-protein interactions. [provided by RefSeq, Aug 2012]
Expression
Ubiquitous expression in placenta (RPKM 12.5), bone marrow (RPKM 10.6) and 25 other tissues See more
Orthologs

Genomic context

See PROSER1 in Genome Data Viewer
Location:
13q13.3
Exon count:
13
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 13 NC_000013.11 (39009865..39038089, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (39584002..39612213, complement)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 26 pseudogene 2 Neighboring gene stomatin like 3 Neighboring gene NHL repeat containing 3 Neighboring gene uncharacterized LOC105370169

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ12661, FLJ23780

General protein information

Preferred Names
proline and serine-rich protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025138.5NP_079414.3  proline and serine-rich protein 1 isoform 1

    See identical proteins and their annotated locations for NP_079414.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AB107354, AL445590, AW294041, BC064348
    Consensus CDS
    CCDS9368.2
    UniProtKB/Swiss-Prot
    Q86XN7
    Related
    ENSP00000332034.4, ENST00000352251.8
    Conserved Domains (1) summary
    pfam14771
    Location:33121
    DUF4476; Domain of unknown function (DUF4476)
  2. NM_170719.3NP_733837.2  proline and serine-rich protein 1 isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AL445590
    Related
    ENSP00000486159.1, ENST00000625998.2
    Conserved Domains (2) summary
    pfam14771
    Location:1299
    DUF4476; Domain of unknown function (DUF4476)
    cl26464
    Location:515917
    Atrophin-1; Atrophin-1 family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p13 Primary Assembly

    Range
    39009865..39038089 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011535239.3XP_011533541.1  proline and serine-rich protein 1 isoform X2

    Conserved Domains (1) summary
    pfam14771
    Location:33121
    DUF4476; Domain of unknown function (DUF4476)
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