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PRR36 proline rich 36 [ Homo sapiens (human) ]

Gene ID: 80164, updated on 16-Jul-2021

Summary

Official Symbol
PRR36provided by HGNC
Official Full Name
proline rich 36provided by HGNC
Primary source
HGNC:HGNC:26172
See related
Ensembl:ENSG00000183248
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene encodes a large protein of unknown function that contains internal regions of low complexity sequence. Alternative splicing results in multiple transcript variants. The transcript structure of the protein-coding variant at this locus is conserved between human and mouse. [provided by RefSeq, Oct 2013]
Expression
Biased expression in brain (RPKM 7.2), prostate (RPKM 1.1) and 4 other tissues See more
Orthologs
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Genomic context

See PRR36 in Genome Data Viewer
Location:
19p13.2
Exon count:
7
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (7868719..7874390, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (7933605..7939275, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene exosome component 3 pseudogene 2 Neighboring gene ecotropic viral integration site 5 like Neighboring gene Sharpr-MPRA regulatory region 8899 Neighboring gene LYPLA2 pseudogene 2 Neighboring gene RNA, 5S ribosomal pseudogene 463

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ22184

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_033809.1 RefSeqGene

    Range
    5052..10723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001190467.2NP_001177396.1  proline-rich protein 36

    See identical proteins and their annotated locations for NP_001177396.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the protein.
    Source sequence(s)
    AC010336, AL537525, KF459711
    Consensus CDS
    CCDS74276.1
    UniProtKB/Swiss-Prot
    Q9H6K5
    Related
    ENSP00000482374.1, ENST00000618550.5
    Conserved Domains (1) summary
    pfam15363
    Location:13031346
    DUF4596; Domain of unknown function (DUF4596)

RNA

  1. NR_104345.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site at an internal exon and lacks an internal segment, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region found in variant 1.
    Source sequence(s)
    AC010336, BE791180, BX452280

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    7868719..7874390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001080403.1: Suppressed sequence

    Description
    NM_001080403.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript.
  2. NM_025094.1: Suppressed sequence

    Description
    NM_025094.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
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