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RPF1 ribosome production factor 1 homolog [ Homo sapiens (human) ]

Gene ID: 80135, updated on 7-Jun-2020

Summary

Official Symbol
RPF1provided by HGNC
Official Full Name
ribosome production factor 1 homologprovided by HGNC
Primary source
HGNC:HGNC:30350
See related
Ensembl:ENSG00000117133
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BXDC5
Expression
Ubiquitous expression in bone marrow (RPKM 14.6), thyroid (RPKM 13.5) and 25 other tissues See more
Orthologs

Genomic context

See RPF1 in Genome Data Viewer
Location:
1p22.3
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (84479266..84498352)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (84944920..84964033)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene urate oxidase (pseudogene) Neighboring gene deoxyribonuclease 2 beta Neighboring gene G protein subunit gamma 5 Neighboring gene spermatogenesis associated 1 Neighboring gene chitobiase Neighboring gene uncharacterized LOC105378819

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ12475, DKFZp761G0415, DKFZp761M0215

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
rRNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
maturation of 5.8S rRNA IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
maturation of LSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
preribosome, large subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
ribosome production factor 1
Names
2310066N05Rik
RNA processing factor 1 (RPF1)
brix domain containing 5
brix domain-containing protein 5
ribosome biogenesis protein RPF1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025065.7NP_079341.2  ribosome production factor 1

    See identical proteins and their annotated locations for NP_079341.2

    Status: VALIDATED

    Source sequence(s)
    AF322053, AL359584, AL359762, AL844170
    Consensus CDS
    CCDS695.1
    UniProtKB/Swiss-Prot
    Q9H9Y2
    Related
    ENSP00000359688.5, ENST00000370654.6
    Conserved Domains (1) summary
    smart00879
    Location:145314
    Brix; The Brix domain is found in a number of eukaryotic proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    84479266..84498352
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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