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BBOF1 basal body orientation factor 1 [ Homo sapiens (human) ]

Gene ID: 80127, updated on 23-Nov-2021

Summary

Official Symbol
BBOF1provided by HGNC
Official Full Name
basal body orientation factor 1provided by HGNC
Primary source
HGNC:HGNC:19855
See related
Ensembl:ENSG00000119636
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FBB10; CCDC176; C14orf45
Expression
Broad expression in kidney (RPKM 30.8), liver (RPKM 16.1) and 17 other tissues See more
Orthologs
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Genomic context

See BBOF1 in Genome Data Viewer
Location:
14q24.3
Exon count:
15
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (74019349..74078351)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (74486052..74532795)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene FAM161 centrosomal protein B Neighboring gene ectonucleoside triphosphate diphosphohydrolase 5 (inactive) Neighboring gene coenzyme Q6, monooxygenase Neighboring gene ribosomal protein L41 pseudogene 4 Neighboring gene Sharpr-MPRA regulatory regions 4216 and 10298 Neighboring gene aldehyde dehydrogenase 6 family member A1 Neighboring gene uncharacterized LOC105370563 Neighboring gene RNY4 pseudogene 21 Neighboring gene lin-52 DREAM MuvB core complex component

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23189

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in motile cilium assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in ciliary basal body ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
basal body-orientation factor 1
Names
coiled-coil domain containing 176
coiled-coil domain-containing protein 176

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_033060.1 RefSeqGene

    Range
    4994..51737
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_025057.3NP_079333.2  basal body-orientation factor 1

    See identical proteins and their annotated locations for NP_079333.2

    Status: VALIDATED

    Source sequence(s)
    AC005484, AK026842, AL834487, BC044808, BC104979, DB484577, DB493409
    Consensus CDS
    CCDS32119.2
    UniProtKB/Swiss-Prot
    Q8ND07
    Related
    ENSP00000377577.3, ENST00000394009.5
    Conserved Domains (1) summary
    pfam14988
    Location:77270
    DUF4515; Domain of unknown function (DUF4515)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    74019349..74078351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011537172.1XP_011535474.1  basal body-orientation factor 1 isoform X3

    Conserved Domains (1) summary
    pfam14988
    Location:77264
    DUF4515; Domain of unknown function (DUF4515)
  2. XM_017021659.1XP_016877148.1  basal body-orientation factor 1 isoform X7

  3. XM_011537171.2XP_011535473.1  basal body-orientation factor 1 isoform X2

    Conserved Domains (1) summary
    pfam14988
    Location:77264
    DUF4515; Domain of unknown function (DUF4515)
  4. XM_011537174.2XP_011535476.1  basal body-orientation factor 1 isoform X4

    Conserved Domains (1) summary
    pfam14988
    Location:77264
    DUF4515; Domain of unknown function (DUF4515)
  5. XM_017021663.1XP_016877152.1  basal body-orientation factor 1 isoform X15

  6. XM_011537170.2XP_011535472.1  basal body-orientation factor 1 isoform X1

    Conserved Domains (1) summary
    pfam14988
    Location:77264
    DUF4515; Domain of unknown function (DUF4515)
  7. XM_005268092.3XP_005268149.1  basal body-orientation factor 1 isoform X5

    Conserved Domains (1) summary
    pfam14988
    Location:77270
    DUF4515; Domain of unknown function (DUF4515)
  8. XM_011537175.2XP_011535477.1  basal body-orientation factor 1 isoform X6

    Conserved Domains (2) summary
    pfam14988
    Location:77216
    DUF4515; Domain of unknown function (DUF4515)
    cl19219
    Location:63181
    DUF342; Protein of unknown function (DUF342)
  9. XM_017021661.1XP_016877150.1  basal body-orientation factor 1 isoform X12

  10. XM_017021660.1XP_016877149.1  basal body-orientation factor 1 isoform X10

  11. XM_011537176.2XP_011535478.1  basal body-orientation factor 1 isoform X8

    Conserved Domains (1) summary
    pfam14988
    Location:4191
    DUF4515; Domain of unknown function (DUF4515)
  12. XM_011537177.2XP_011535479.1  basal body-orientation factor 1 isoform X9

    See identical proteins and their annotated locations for XP_011535479.1

    Conserved Domains (1) summary
    pfam14988
    Location:1124
    DUF4515; Domain of unknown function (DUF4515)
  13. XM_005268098.4XP_005268155.1  basal body-orientation factor 1 isoform X16

    See identical proteins and their annotated locations for XP_005268155.1

  14. XM_011537179.2XP_011535481.1  basal body-orientation factor 1 isoform X11

    Conserved Domains (2) summary
    pfam05483
    Location:89281
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam14988
    Location:160
    DUF4515; Domain of unknown function (DUF4515)
  15. XM_017021662.1XP_016877151.1  basal body-orientation factor 1 isoform X14

  16. XM_011537178.2XP_011535480.1  basal body-orientation factor 1 isoform X9

    See identical proteins and their annotated locations for XP_011535480.1

    Conserved Domains (1) summary
    pfam14988
    Location:1124
    DUF4515; Domain of unknown function (DUF4515)
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