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MZT2B mitotic spindle organizing protein 2B [ Homo sapiens (human) ]

Gene ID: 80097, updated on 23-Nov-2021

Summary

Official Symbol
MZT2Bprovided by HGNC
Official Full Name
mitotic spindle organizing protein 2Bprovided by HGNC
Primary source
HGNC:HGNC:25886
See related
Ensembl:ENSG00000152082 MIM:613450
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM128B; MOZART2B
Expression
Ubiquitous expression in fat (RPKM 10.8), colon (RPKM 10.5) and 25 other tissues See more
Orthologs
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Genomic context

See MZT2B in Genome Data Viewer
Location:
2q21.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (130182262..130190727)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (130939835..130948300)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 15 pseudogene 9 Neighboring gene coiled-coil domain containing 74B Neighboring gene sphingomyelin phosphodiesterase 4 Neighboring gene tubulin alpha 3e Neighboring gene ras homolog family member Q pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14346, MGC87017

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
part_of gamma-tubulin large complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
is_active_in spindle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in spindle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
mitotic-spindle organizing protein 2B
Names
family with sequence similarity 128, member B
mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330282.2NP_001317211.1  mitotic-spindle organizing protein 2B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC018804
    Consensus CDS
    CCDS82511.1
    UniProtKB/TrEMBL
    B8ZZ87
    Related
    ENSP00000386419.1, ENST00000409255.1
    Conserved Domains (1) summary
    pfam12926
    Location:996
    MOZART2; Mitotic-spindle organizing gamma-tubulin ring associated
  2. NM_001330284.2NP_001317213.1  mitotic-spindle organizing protein 2B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC018804
    Related
    ENSP00000404629.1, ENST00000455239.1
    Conserved Domains (1) summary
    pfam12926
    Location:957
    MOZART2; Mitotic-spindle organizing gamma-tubulin ring associated
  3. NM_025029.5NP_079305.2  mitotic-spindle organizing protein 2B isoform 2

    See identical proteins and their annotated locations for NP_079305.2

    Status: VALIDATED

    Source sequence(s)
    AC018804, BC014255
    Consensus CDS
    CCDS2157.1
    UniProtKB/Swiss-Prot
    Q6NZ67
    Related
    ENSP00000281871.7, ENST00000281871.11
    Conserved Domains (1) summary
    pfam12926
    Location:996
    MOZART2; Mitotic-spindle organizing gamma-tubulin ring associated

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    130182262..130190727
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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