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DNAJC22 DnaJ heat shock protein family (Hsp40) member C22 [ Homo sapiens (human) ]

Gene ID: 79962, updated on 1-Jun-2020

Summary

Official Symbol
DNAJC22provided by HGNC
Official Full Name
DnaJ heat shock protein family (Hsp40) member C22provided by HGNC
Primary source
HGNC:HGNC:25802
See related
Ensembl:ENSG00000178401
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
wus
Expression
Biased expression in liver (RPKM 7.7), duodenum (RPKM 7.3) and 10 other tissues See more
Orthologs

Genomic context

See DNAJC22 in Genome Data Viewer
Location:
12q13.12
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (49346888..49353690)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (49740721..49747467)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101927267 Neighboring gene trophinin associated protein Neighboring gene complement C1q like 4 Neighboring gene spermatogenesis associated serine rich 2 Neighboring gene FGFR1 oncogene partner 2 pseudogene Neighboring gene uncharacterized LOC105369761 Neighboring gene potassium voltage-gated channel subfamily H member 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of DnaJ (Hsp40) homolog, subfamily C, member 22 (DNAJC22) by shRNA library screening inhibits HIV-1 replication in cultured Jurkat T-cells PubMed

Go to the HIV-1, Human Interaction Database

General gene information

Markers

Homology

Clone Names

  • FLJ13236

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
dnaJ homolog subfamily C member 22
Names
DnaJ (Hsp40) homolog, subfamily C, member 22
wurst homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304944.2NP_001291873.1  dnaJ homolog subfamily C member 22

    See identical proteins and their annotated locations for NP_001291873.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC125611, AK055747
    Consensus CDS
    CCDS8785.1
    UniProtKB/Swiss-Prot
    Q8N4W6
    UniProtKB/TrEMBL
    A0A024R0Z2
    Related
    ENSP00000446830.1, ENST00000549441.7
    Conserved Domains (1) summary
    smart00271
    Location:278335
    DnaJ; DnaJ molecular chaperone homology domain
  2. NM_024902.4NP_079178.2  dnaJ homolog subfamily C member 22

    See identical proteins and their annotated locations for NP_079178.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC125611, AK055747, BC033236
    Consensus CDS
    CCDS8785.1
    UniProtKB/Swiss-Prot
    Q8N4W6
    UniProtKB/TrEMBL
    A0A024R0Z2
    Related
    ENSP00000378508.2, ENST00000395069.3
    Conserved Domains (1) summary
    smart00271
    Location:278335
    DnaJ; DnaJ molecular chaperone homology domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    49346888..49353690
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005269156.2XP_005269213.1  dnaJ homolog subfamily C member 22 isoform X2

  2. XM_005269155.2XP_005269212.1  dnaJ homolog subfamily C member 22 isoform X1

  3. XM_005269157.2XP_005269214.1  dnaJ homolog subfamily C member 22 isoform X3

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