Format

Send to:

Choose Destination

ERMP1 endoplasmic reticulum metallopeptidase 1 [ Homo sapiens (human) ]

Gene ID: 79956, updated on 24-Nov-2020

Summary

Official Symbol
ERMP1provided by HGNC
Official Full Name
endoplasmic reticulum metallopeptidase 1provided by HGNC
Primary source
HGNC:HGNC:23703
See related
Ensembl:ENSG00000099219 MIM:611156
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FXNA; KIAA1815; bA207C16.3
Expression
Ubiquitous expression in thyroid (RPKM 22.8), kidney (RPKM 19.4) and 24 other tissues See more
Orthologs

Genomic context

See ERMP1 in Genome Data Viewer
Location:
9p24.1
Exon count:
20
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (5764061..5867091, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (5784572..5833081, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene CD274 molecule Neighboring gene programmed cell death 1 ligand 2 Neighboring gene RIC1 homolog, RAB6A GEF complex partner 1 Neighboring gene Sharpr-MPRA regulatory region 2314 Neighboring gene KIAA2026 Neighboring gene adenylate kinase 4 pseudogene 4 Neighboring gene melan-A Neighboring gene microRNA 4665

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1815

Gene Ontology Provided by GOA

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cellular response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
endoplasmic reticulum unfolded protein response IMP
Inferred from Mutant Phenotype
more info
PubMed 
proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane HDA PubMed 

General protein information

Preferred Names
endoplasmic reticulum metallopeptidase 1
Names
Felix-ina
aminopeptidase Fxna

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024896.3NP_079172.2  endoplasmic reticulum metallopeptidase 1

    See identical proteins and their annotated locations for NP_079172.2

    Status: VALIDATED

    Source sequence(s)
    AB058718, AK026962, AK093217, AK127218, AK172831, AL365360, AL834191, AW295384, BC031630, CN390893
    Consensus CDS
    CCDS34983.1
    UniProtKB/Swiss-Prot
    Q7Z2K6
    UniProtKB/TrEMBL
    Q6ZMD3
    Related
    ENSP00000340427.5, ENST00000339450.10
    Conserved Domains (1) summary
    cd03875
    Location:104412
    M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    5764061..5867091 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005251587.2XP_005251644.1  endoplasmic reticulum metallopeptidase 1 isoform X2

    Conserved Domains (1) summary
    cd03875
    Location:104412
    M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1
  2. XM_017015139.2XP_016870628.1  endoplasmic reticulum metallopeptidase 1 isoform X1

RNA

  1. XR_428431.3 RNA Sequence

  2. XR_929337.2 RNA Sequence

  3. XR_929340.2 RNA Sequence

  4. XR_001746382.2 RNA Sequence

  5. XR_929338.2 RNA Sequence

Support Center