Format

Send to:

Choose Destination

GGNBP2 gametogenetin binding protein 2 [ Homo sapiens (human) ]

Gene ID: 79893, updated on 5-Jul-2020

Summary

Official Symbol
GGNBP2provided by HGNC
Official Full Name
gametogenetin binding protein 2provided by HGNC
Primary source
HGNC:HGNC:19357
See related
Ensembl:ENSG00000278311 MIM:612275
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DIF3; LZK1; DIF-3; LCRG1; ZFP403; ZNF403
Expression
Ubiquitous expression in testis (RPKM 42.4), bone marrow (RPKM 29.3) and 25 other tissues See more
Orthologs

Genomic context

See GGNBP2 in Genome Data Viewer
Location:
17q12
Exon count:
14
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (36544913..36589848)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (34900737..34946278)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene RNA, 5S ribosomal pseudogene 439 Neighboring gene zinc finger HIT-type containing 3 Neighboring gene myosin XIX Neighboring gene phosphatidylinositol glycan anchor biosynthesis class W Neighboring gene ribosomal protein S2 pseudogene 50 Neighboring gene uncharacterized LOC107985031 Neighboring gene dehydrogenase/reductase 11 Neighboring gene mitochondrial rRNA methyltransferase 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21230, FLJ22561, FLJ42090

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
labyrinthine layer blood vessel development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of cell proliferation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
negative regulation of peptidyl-serine phosphorylation of STAT protein IEA
Inferred from Electronic Annotation
more info
 
negative regulation of protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
negative regulation of tyrosine phosphorylation of STAT protein IEA
Inferred from Electronic Annotation
more info
 
spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
gametogenetin-binding protein 2
Names
C3HC4-type zinc finger protein
laryngeal carcinoma related gene 1
laryngeal carcinoma-related protein 1
zinc finger protein 403

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024835.5NP_079111.1  gametogenetin-binding protein 2

    See identical proteins and their annotated locations for NP_079111.1

    Status: VALIDATED

    Source sequence(s)
    AF126964, BC137491, DA494492
    Consensus CDS
    CCDS11314.1
    UniProtKB/Swiss-Prot
    Q9H3C7
    Related
    ENSP00000478220.1, ENST00000613102.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    36544913..36589848
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005257689.3XP_005257746.1  gametogenetin-binding protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005257746.1

  2. XM_011525266.2XP_011523568.1  gametogenetin-binding protein 2 isoform X4

    See identical proteins and their annotated locations for XP_011523568.1

  3. XM_011525265.3XP_011523567.1  gametogenetin-binding protein 2 isoform X2

    See identical proteins and their annotated locations for XP_011523567.1

  4. XM_017025107.1XP_016880596.1  gametogenetin-binding protein 2 isoform X3

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187614.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    779823..825343
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center