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ZNF671 zinc finger protein 671 [ Homo sapiens (human) ]

Gene ID: 79891, updated on 27-Nov-2024

Summary

Official Symbol
ZNF671provided by HGNC
Official Full Name
zinc finger protein 671provided by HGNC
Primary source
HGNC:HGNC:26279
See related
Ensembl:ENSG00000083814 AllianceGenome:HGNC:26279
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in spleen (RPKM 4.7), lymph node (RPKM 4.6) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF671 in Genome Data Viewer
Location:
19q13.43
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (57719751..57727624, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (60816684..60824556, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (58231119..58238992, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 154 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:58220160-58220799 Neighboring gene uncharacterized LOC124904783 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:58238691-58239191 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:58239145-58239370 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15157 Neighboring gene zinc finger protein 776 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:58280768-58281307 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15159 Neighboring gene zinc finger protein 586

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ23506

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321375.2NP_001308304.1  zinc finger protein 671 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC003006, AK293680, DB132318
    UniProtKB/TrEMBL
    B7Z1N1
    Conserved Domains (4) summary
    COG5048
    Location:187345
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:273293
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:271293
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:202226
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001321376.2NP_001308305.1  zinc finger protein 671 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC003006, AK091421, DB132318
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:208366
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:294314
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:292314
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:223247
    zf-H2C2_2; Zinc-finger double domain
  3. NM_024833.3NP_079109.2  zinc finger protein 671 isoform 1

    See identical proteins and their annotated locations for NP_079109.2

    Status: VALIDATED

    Source sequence(s)
    AK027159, BC025728, DB104548
    Consensus CDS
    CCDS12961.1
    UniProtKB/Swiss-Prot
    A6NF07, Q8TAW3, Q9H5E9
    Related
    ENSP00000321848.5, ENST00000317398.10
    Conserved Domains (6) summary
    smart00349
    Location:49109
    KRAB; krueppel associated box
    COG5048
    Location:285443
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:371391
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:369391
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:4988
    KRAB; KRAB box
    pfam13465
    Location:300324
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    57719751..57727624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017027314.2XP_016882803.1  zinc finger protein 671 isoform X1

    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:208366
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:294314
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:292314
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:223247
    zf-H2C2_2; Zinc-finger double domain

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    60816684..60824556 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054322203.1XP_054178178.1  zinc finger protein 671 isoform X1