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CAAP1 caspase activity and apoptosis inhibitor 1 [ Homo sapiens (human) ]

Gene ID: 79886, updated on 21-Dec-2019

Summary

Official Symbol
CAAP1provided by HGNC
Official Full Name
caspase activity and apoptosis inhibitor 1provided by HGNC
Primary source
HGNC:HGNC:25834
See related
Ensembl:ENSG00000120159
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CAAP; C9orf82
Expression
Ubiquitous expression in thyroid (RPKM 14.1), adrenal (RPKM 11.5) and 25 other tissues See more
Orthologs

Genomic context

See CAAP1 in Genome Data Viewer
Location:
9p21.2
Exon count:
7
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (26840685..26892828, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (26840683..26892826, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376000 Neighboring gene uncharacterized LOC107987028 Neighboring gene RNA, 7SL, cytoplasmic 100, pseudogene Neighboring gene phospholipase A2 activating protein Neighboring gene intraflagellar transport 74

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13657

General protein information

Preferred Names
caspase activity and apoptosis inhibitor 1
Names
conserved anti-apoptotic protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167575.1NP_001161047.1  caspase activity and apoptosis inhibitor 1 isoform 2

    See identical proteins and their annotated locations for NP_001161047.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice junction at the 3' end of the first exon compared to variant 1, that causes a frameshift. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AF131768, BC071953, BP228742, BP374752
    Consensus CDS
    CCDS55299.1
    UniProtKB/Swiss-Prot
    Q9H8G2
    Related
    ENSP00000487373.1, ENST00000625311.1
    Conserved Domains (1) summary
    pfam15335
    Location:150
    CAAP1; Caspase activity and apoptosis inhibitor 1
  2. NM_024828.4NP_079104.3  caspase activity and apoptosis inhibitor 1 isoform 1

    See identical proteins and their annotated locations for NP_079104.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AF131768, BC071953, BP228742
    Consensus CDS
    CCDS6516.1
    UniProtKB/Swiss-Prot
    Q9H8G2
    Related
    ENSP00000369431.3, ENST00000333916.8
    Conserved Domains (1) summary
    pfam15335
    Location:134195
    CAAP1; Caspase activity and apoptosis inhibitor 1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    26840685..26892828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001746381.1 RNA Sequence

    Related
    ENST00000650615.1
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